[HTML][HTML] Update on neutrophil function in severe inflammation

E Mortaz, SD Alipoor, IM Adcock, S Mumby… - Frontiers in …, 2018 - frontiersin.org
Neutrophils are main players in the effector phase of the host defense against micro-
organisms and have a major role in the innate immune response. Neutrophils show …

Neutrophil extracellular traps in the second decade

V Brinkmann - Journal of innate immunity, 2018 - karger.com
Nearly 15 years after the first description of neutrophil extracellular traps (NETs), our
knowledge concerning this structure has expanded considerably. Initially, NETs were …

Neutrophil extracellular traps: double-edged swords of innate immunity

MJ Kaplan, M Radic - The Journal of Immunology, 2012 - journals.aai.org
Spectacular images of neutrophils ejecting nuclear chromatin and bactericidal proteins, in
response to microbes, were first reported in 2004. As externalized chromatin could entangle …

Neutrophil extracellular traps: is immunity the second function of chromatin?

V Brinkmann, A Zychlinsky - Journal of cell biology, 2012 - rupress.org
Neutrophil extracellular traps (NETs) are made of processed chromatin bound to granular
and selected cytoplasmic proteins. NETs are released by white blood cells called …

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

CF Urban, D Ermert, M Schmid, U Abu-Abed… - PLoS …, 2009 - journals.plos.org
Neutrophils are the first line of defense at the site of an infection. They encounter and kill
microbes intracellularly upon phagocytosis or extracellularly by degranulation of …

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

Q Remijsen, TW Kuijpers, E Wirawan… - Cell Death & …, 2011 - nature.com
Neutrophil extracellular traps (NETs) are chromatin structures loaded with antimicrobial
molecules. They can trap and kill various bacterial, fungal and protozoal pathogens, and …

NETs: a new strategy for using old weapons

V Papayannopoulos, A Zychlinsky - Trends in immunology, 2009 - cell.com
As key players in the host innate immune response, neutrophils are recruited to sites of
infection and constitute the first line of defense. They employ three strategies to eliminate …

Neutrophils: Cinderella of innate immune system

V Kumar, A Sharma - International immunopharmacology, 2010 - Elsevier
Neutrophils are the first line of innate immune defense against infectious diseases.
However, since their discovery by Elie Metchnikoff, they have always been considered …

To NET or not to NET: current opinions and state of the science regarding the formation of neutrophil extracellular traps

S Boeltz, P Amini, HJ Anders, F Andrade… - Cell Death & …, 2019 - nature.com
Since the discovery and definition of neutrophil extracellular traps (NETs) 14 years ago,
numerous characteristics and physiological functions of NETs have been uncovered …

The role of reactive oxygen species (ROS) in the formation of extracellular traps (ETs) in humans

W Stoiber, A Obermayer, P Steinbacher… - Biomolecules, 2015 - mdpi.com
Extracellular traps (ETs) are reticulate structures of extracellular DNA associated with
antimicrobial molecules. Their formation by phagocytes (mainly by neutrophils: NETs) has …