Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …

The Flavivirus genus comprises many viruses (including dengue, Zika, West Nile and yellow
fever viruses) which constitute important public health concerns worldwide. For several of …

Protein-protein interactions (PPIs) and multi-protein complexes perform central roles in the
cellular systems of all living organisms. In humans, disruptions of the normal patterns of PPIs …

Flaviviruses limit the cell stress response by preventing the formation of stress granules
(SGs) and modulate viral gene expression by subverting different proteins involved in the …

Components of cytoplasmic processing bodies (P-bodies) and stress granules can be
subverted during viral infections to modulate viral gene expression. Because hepatitis C …

More than 170 million people worldwide are infected with the hepatitis C virus (HCV), for
which future therapies are expected to rely upon a combination of oral antivirals. For a …

To identify new regulators of antiviral innate immunity, we completed the first genome-wide
gene silencing screen assessing the transcriptional response at the interferon-β (IFNB1) …

Flaviviridae infections represent a major global health burden. By deciphering mechanistic
aspects of hepatitis C virus (HCV)-host interactions, one could discover common strategy for …

LINE-1 (L1) retrotransposons are autonomous transposable elements that can affect gene
expression and genome integrity. Potential consequences of exogenous viral infections for …

Hepatitis C virus (HCV) orchestrates the different stages of its life cycle in time and space
through the sequential participation of HCV proteins and cellular machineries; hence, these …