Osteosarcoma is the most common primary bone malignancy in adolescents. Its high
propensity to metastasize is the leading cause for treatment failure and poor prognosis …

Melatonin is a pleotropic molecule with numerous biological activities. Epidemiological and
experimental studies have documented that melatonin could inhibit different types of cancer …

Zinc (Zn) is one of the most important trace elements in the human body and plays a key role
in various physiological processes, especially in bone metabolism. Zn-containing materials …

Cancers are serious life-threatening diseases which annually are responsible for millions of
deaths across the world. Despite many developments in therapeutic approaches for affected …

The vascular dysfunction of ovarian cancer (OC) contributes to the chemotherapeutic
resistance. In this study, we aimed to explore whether exosome-mediated angiogenesis …

The present study aims to analyze the expression of long noncoding RNA (lncRNA)
metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) in human osteosarcoma …

Purpose Bone diseases account for an enormous cost burden on health systems. Bone
disorders are considered as age-dependent diseases. The aging of world population has …

Despite, melatonin is mainly known as a regulatory factor for circadian rhythm, its notable
role in other fundamental biological processes, such as redox homeostasis and …

The metastasis and angiogenesis of breast cancer has always been a difficult problem for
treatment. It has recently been discovered that Von Willebrand Factor (vWF), in addition to …

Under endoplasmic reticulum (ER) stress, tumor plays multifaceted roles in endothelial cell
dysfunction through secreting exosomal miRNAs. However, for the head and neck …