Carcinogenic human papillomavirus infection

M Schiffman, J Doorbar, N Wentzensen… - Nature reviews Disease …, 2016 - nature.com
Infections with human papillomavirus (HPV) are common and transmitted by direct contact.
Although the great majority of infections resolve within 2 years, 13 phylogenetically related …

Human papillomaviruses; epithelial tropisms, and the development of neoplasia

N Egawa, K Egawa, H Griffin, J Doorbar - Viruses, 2015 - mdpi.com
Papillomaviruses have evolved over many millions of years to propagate themselves at
specific epithelial niches in a range of different host species. This has led to the great …

Human papillomavirus in the setting of immunodeficiency: Pathogenesis and the emergence of next-generation therapies to reduce the high associated cancer risk

RV Hewavisenti, J Arena, CL Ahlenstiel… - Frontiers in …, 2023 - frontiersin.org
Human papillomavirus (HPV), a common sexually transmitted virus infecting mucosal or
cutaneous stratified epithelia, is implicated in the rising of associated cancers worldwide …

[HTML][HTML] Human papillomavirus genome variants

RD Burk, A Harari, Z Chen - Virology, 2013 - Elsevier
Amongst the human papillomaviruses (HPVs), the genus Alphapapillomavirus contains HPV
types that are uniquely pathogenic. They can be classified into species and types based on …

Human papillomavirus genomics: Understanding carcinogenicity

CW Nelson, L Mirabello - Tumour Virus Research, 2023 - Elsevier
Human papillomavirus (HPV) causes virtually all cervical cancers and many cancers at other
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …

[HTML][HTML] Evolution of the papillomaviridae

K Van Doorslaer - Virology, 2013 - Elsevier
Viruses belonging to the Papillomaviridae family have been isolated from a variety of
mammals, birds and non-avian reptiles. It is likely that most, if not all, amniotes carry a broad …

HPV16 sublineage associations with histology-specific cancer risk using HPV whole-genome sequences in 3200 women

L Mirabello, M Yeager, M Cullen… - JNCI: Journal of the …, 2016 - academic.oup.com
Background: HPV16 is a common sexually transmitted infection although few infections lead
to cervical precancer/cancer; we cannot distinguish nor mechanistically explain why only …

A population-based prospective study of carcinogenic human papillomavirus variant lineages, viral persistence, and cervical neoplasia

M Schiffman, AC Rodriguez, Z Chen, S Wacholder… - Cancer research, 2010 - AACR
Human papillomavirus (HPV) types differ profoundly in cervical carcinogenicity. For the most
carcinogenic type HPV16, variant lineages representing further evolutionary divergence …

FOXM1 (Forkhead box M1) in tumorigenesis: overexpression in human cancer, implication in tumorigenesis, oncogenic functions, tumor-suppressive properties, and …

I Wierstra - Advances in cancer research, 2013 - Elsevier
Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor
and is also intimately involved in tumorigenesis. FOXM1 stimulates cell proliferation and cell …

Molecular basis of pterygium development

E Cardenas-Cantu, J Zavala, J Valenzuela… - Seminars in …, 2016 - Taylor & Francis
Pterygium pathogenesis is mainly related to UV light exposure. However, the exact
mechanisms by which it is formed have not been elucidated. Clinical advances in surgical …