Artificial cornea: past, current, and future directions

G Holland, A Pandit, L Sánchez-Abella, A Haiek… - Frontiers in …, 2021 - frontiersin.org
Corneal diseases are a leading cause of blindness with an estimated 10 million patients
diagnosed with bilateral corneal blindness worldwide. Corneal transplantation is highly …

The Boston Keratoprosthesis—the first 50 years: some reminiscences

C Dohlman - Annual Review of Vision Science, 2022 - annualreviews.org
Millions of people worldwide are bilaterally blind due to corneal diseases including
infectious etiologies, trauma, and chemical injuries. While corneal transplantation can …

Alternatives to eye bank native tissue for corneal stromal replacement

I Brunette, CJ Roberts, F Vidal… - Progress in retinal and …, 2017 - Elsevier
Corneal blindness is a major cause of blindness in the world and corneal transplantation is
the only widely accepted treatment to restore sight in these eyes. However, it is becoming …

Biocompatibility of a fish scale-derived artificial cornea: cytotoxicity, cellular adhesion and phenotype, and in vivo immunogenicity

TH Van Essen, L Van Zijl, T Possemiers, AA Mulder… - Biomaterials, 2016 - Elsevier
Purpose To determine whether a fish scale-derived collagen matrix (FSCM) meets the basic
criteria to serve as an artificial cornea, as determined with in vitro and in vivo tests. Methods …

Boston type 1 keratoprosthesis versus repeat donor keratoplasty for corneal graft failure: a systematic review and meta-analysis

S Ahmad, PM Mathews, K Lindsley, M Alkharashi… - Ophthalmology, 2016 - Elsevier
Purpose To compare repeat penetrating keratoplasty (PK) with Boston type I
keratoprosthesis (KPro) implantation for full-thickness donor corneal graft failure. Design …

Infectious endophthalmitis in Boston keratoprosthesis: incidence and prevention

I Behlau, KV Martin, JN Martin… - Acta …, 2014 - Wiley Online Library
Purpose To determine the cumulative worldwide incidence of infectious endophthalmitis and
associated vision loss after Boston keratoprosthesis (B‐KP ro) Type I/II implantation and to …

UV cross-linking of donor corneas confers resistance to keratolysis

SN Arafat, MC Robert, AN Shukla, CH Dohlman… - Cornea, 2014 - journals.lww.com
Purpose: The aim of this study was to develop a modified ex vivo corneal cross-linking
method that increases stromal resistance to enzymatic degradation for use as a carrier for …

Artificial corneas versus donor corneas for repeat corneal transplants

EK Akpek, M Alkharashi, FS Hwang… - Cochrane Database …, 2014 - cochranelibrary.com
Background Individuals who have failed one or more full thickness penetrating
keratoplasties (PKs) may be offered repeat corneal surgery using an artificial or donor …

The Boston Keratoprosthesis type 1 as primary penetrating corneal procedure

R Fadous, S Levallois-Gignac, L Vaillancourt… - British Journal of …, 2015 - bjo.bmj.com
Background/aims Penetrating keratoplasty (PK) has a poor prognosis in certain corneal eye
diseases. The safety and efficacy of Boston type 1 Keratoprosthesis (KPro) surgery as a …

Complications associated with Boston keratoprosthesis type 1 and glaucoma drainage devices

MC Robert, V Pomerleau… - British Journal of …, 2013 - bjo.bmj.com
Background/aims To compare the complications leading to best-corrected visual acuity
(BCVA) loss in patients with Boston keratoprosthesis type 1 (KPro) and glaucoma drainage …