Grading of invasive breast carcinoma: the way forward

C Van Dooijeweert, PJ Van Diest, IO Ellis - Virchows Archiv, 2022 - Springer
Histologic grading has been a simple and inexpensive method to assess tumor behavior
and prognosis of invasive breast cancer grading, thereby identifying patients at risk for …

Survival disparities in US Black compared to White women with hormone receptor positive-HER2 negative breast cancer

LA Lovejoy, CD Shriver, S Haricharan… - International journal of …, 2023 - mdpi.com
Black women in the US have significantly higher breast cancer mortality than White women.
Within biomarker-defined tumor subtypes, disparate outcomes seem to be limited to women …

Integration of clinical features and deep learning on pathology for the prediction of breast cancer recurrence assays and risk of recurrence

FM Howard, J Dolezal, S Kochanny, G Khramtsova… - NPJ Breast …, 2023 - nature.com
Gene expression-based recurrence assays are strongly recommended to guide the use of
chemotherapy in hormone receptor-positive, HER2-negative breast cancer, but such testing …

Race and delays in breast cancer treatment across the care continuum in the Carolina Breast Cancer Study

KE Reeder‐Hayes, SE Mayer, AF Olshan… - Cancer, 2019 - Wiley Online Library
Background After controlling for baseline disease factors, researchers have found that black
women have worse breast cancer survival, and this suggests that treatment differences may …

Trend and survival benefit of Oncotype DX use among female hormone receptor-positive breast cancer patients in 17 SEER registries, 2004–2015

L Zhang, MC Hsieh, V Petkov, Q Yu, Y Chiu… - Breast cancer research …, 2020 - Springer
Purpose To examine (1) the trend and associated factors of Oncotype DX (ODX) use among
hormone receptor-positive (HR+) breast cancer (BC) patients in 2004–2015;(2) the trend of …

Propensity score analysis of the prognostic value of genomic assays for breast cancer in diverse populations using the National Cancer Data Base

A Ibraheem, OI Olopade, D Huo - Cancer, 2020 - Wiley Online Library
Background Genomic assays such as Oncotype Dx (ODX) and MammaPrint are used for risk‐
adapted treatment decisions among patients with early breast cancer. However, to the …

Validation of the RSClin risk calculator in the National Cancer Data Base

AGL Vannier, A Dhungana, F Zhao, N Chen… - Cancer, 2024 - Wiley Online Library
Background Guidelines recommend the use of genomic assays such as OncotypeDx to aid
in decisions regarding the use of chemotherapy for hormone receptor–positive, HER2 …

Outcomes of hormone-receptor positive, HER2-negative breast cancers by race and tumor biological features

HC Benefield, KE Reeder-Hayes… - JNCI cancer …, 2021 - academic.oup.com
Background Black women have higher hormone receptor positive (HR+) breast cancer
mortality than White women. Early recurrence rates differ by race, but little is known about …

Disparities in OncotypeDX testing and subsequent chemotherapy receipt by geography and socioeconomic status

SC Van Alsten, MR Dunn, AM Hamilton, JM Ivory… - … Biomarkers & Prevention, 2024 - AACR
Background: OncotypeDx is a prognostic and predictive genomic assay used in early-stage
hormone receptor–positive, HER2−(HR+/HER2−) breast cancer. It is used to inform adjuvant …

[图书][B] Statistical methods for mediation, confounding and moderation analysis using R and SAS

Q Yu, B Li - 2022 - taylorfrancis.com
Third-variable effect refers to the effect transmitted by third-variables that intervene in the
relationship between an exposure and a response variable. Differentiating between the …