Chronic inflammatory airway diseases, including asthma, chronic rhinosinusitis, eosinophilic
COPD and allergic rhinitis are a global health concern. Despite the coexistence of these …

Patients with severe asthma represent a minority of the total asthma population, but carry a
majority of the morbidity and healthcare costs. Achieving better asthma control in this group …

Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …

Rationale: Reducing asthma exacerbation frequency is an important criterion for approval of
asthma therapies, but the clinical features of exacerbation-prone asthma (EPA) remain …

Background: The assessment of asthma control is pivotal to the evaluation of treatment
response in individuals and in clinical trials. Previously, asthma control, severity, and …

To cite this article: Jarvis D, Newson R, Lotvall J, Hastan D, Tomassen P, Keil T, Gjomarkaj
M, Forsberg B, Gunnbjornsdottir M, Minov J, Brozek G, Dahlen SE, Toskala E, Kowalski ML …

Background The Centers for Disease Control and Prevention advises that patients with
moderate to severe asthma belong to a high-risk group that is susceptible to severe …

Clinical asthma is very widely assumed to be the net result of excessive inflammation driven
by aberrant T-helper-2 (Th2) immunity that leads to inflamed, remodelled airways and then …

Objective: To review the evidence for an association between depression and anxiety and
the National Health Priority Area conditions—heart disease, stroke, diabetes mellitus …

Abstract The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a
World Health Organization workshop in 1999. The initial goals were (1) to propose a new …