Objectives Type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) are common diseases
that frequently co-exist, along with overweight/obesity. While the mechanical impact of …

The knee is the joint most frequently involved in osteoarthritis and represents a significant
contributor to patient morbidity and impaired functional status. Major risk factors include …

Osteoarthritis (OA) is a prevalent progressive disease that frequently coexists with obesity.
For several decades, OA was thought to be the result of ageing and mechanical stress on …

Type 2 diabetes mellitus (T2DM), Overweight (obesity), and osteoarthritis (OA) are chronic
disorders that commonly coexist. While the mechanical effects of increased body weight on …

Introduction Today, not only the existence of an interrelation between obesity/adipositas and
osteoarthritis (OA) but also the association of OA and diabetes mellitus (DM) are widely …

Background An association between metabolic syndrome (MeS) and osteoarthritis (OA) has
been reported in recent years; however, conflicting findings have been reported regarding …

Objective Patients with Type 2 Diabetes mellitus (T2DM) are prone to osteoarthritis (OA).
Matrix metalloproteinases (MMPs), an essential modulator in cartilage matrix homeostasis …

Osteoarthritis (OA), the most common form of arthritis, may be triggered by improper
secretion of circadian clock-regulated hormones, such as melatonin, thyroid-stimulating …

Phthalates have extensive existence in the living environment of human, probably tightly
associated with multiple human diseases. The present study aimed to exploratorily …

Objectives. With increasing evidence regarding the metabolic basis of osteoarthritis (OA), we
studied the relationship between adipose tissue and OA. Methods. This study is part of an …