A disease spectrum for ITPA variation: advances in biochemical and clinical research
NE Burgis - Journal of Biomedical Science, 2016 - Springer
Human ITPase (encoded by the ITPA gene) is a protective enzyme which acts to exclude
noncanonical (deoxy) nucleoside triphosphates ((d) NTPs) such as (deoxy) inosine 5 …
noncanonical (deoxy) nucleoside triphosphates ((d) NTPs) such as (deoxy) inosine 5 …
Pharmacogenetics of ribavirin-induced anemia in HCV patients
Dual therapy (pegylated interferon plus ribavirin) was considered the standard of care for
hepatitis C virus (HCV) treatment until 2011, when the first-wave direct-acting antivirals were …
hepatitis C virus (HCV) treatment until 2011, when the first-wave direct-acting antivirals were …
Performance of acoustic radiation force impulse elastography for staging liver fibrosis in patients with chronic hepatitis C after viral eradication
SH Chen, HC Lai, IP Chiang, WP Su… - Clinical Infectious …, 2020 - academic.oup.com
Background Data on noninvasive liver fibrosis staging after viral eradication are unclear.
This histology-based study validated the performance of liver stiffness (LS) measurements …
This histology-based study validated the performance of liver stiffness (LS) measurements …
Changes in liver stiffness measurement using acoustic radiation force impulse elastography after antiviral therapy in patients with chronic hepatitis C
Background To compare on-treatment and off-treatment parameters acquired using acoustic
radiation force impulse elastography, the Fibrosis-4 (FIB-4) index, and aspartate …
radiation force impulse elastography, the Fibrosis-4 (FIB-4) index, and aspartate …
Inosine triphosphate pyrophosphatase (ITPase): Functions, mutations, polymorphisms and its impact on cancer therapies
MA Zamzami - Cells, 2022 - mdpi.com
Inosine triphosphate pyrophosphatase (ITPase) is an enzyme encoded by the ITPA gene
and functions to prevent the incorporation of noncanonical purine nucleotides into DNA and …
and functions to prevent the incorporation of noncanonical purine nucleotides into DNA and …
Liver fibrosis regression correlates with downregulation in liver angiogenesis in chronic hepatitis C through viral eradication
Objectives The impact of viral eradication on hepatic angiogenesis is unknown. This study
aimed to analyze the correlations of liver angiogenesis with liver fibrosis progression or …
aimed to analyze the correlations of liver angiogenesis with liver fibrosis progression or …
A comprehensive index for predicting risk of anemia from patients' diagnoses
This article demonstrates how time-dependent, interacting, and repeating risk factors can be
used to create more accurate predictive medicine. In particular, we show how emergence of …
used to create more accurate predictive medicine. In particular, we show how emergence of …
[HTML][HTML] The ITPA and C20orf194 polymorphisms and hematological changes during treatment with pegylated-interferon plus ribavirin in patients with chronic hepatitis …
Background: It has been found that ITPase deficiency is caused by ITPA gene
polymorphisms. It was observed that ITPA polymorphisms have impact on hematological …
polymorphisms. It was observed that ITPA polymorphisms have impact on hematological …
A facile PCR‐RFLP method for genotyping of ITPA rs1127354 and rs7270101 polymorphisms
Background Inosine triphosphate pyrophosphatase (ITPA) gene single nucleotide
polymorphisms (SNP s), rs1127354 and rs7270101, may cause a functional impairment in …
polymorphisms (SNP s), rs1127354 and rs7270101, may cause a functional impairment in …