Eph receptors constitute the largest family of tyrosine kinase receptors and, together with
their plasma-membrane-bound ephrin ligands, have many important functions during …

▪ Abstract The Eph receptors are the largest known family of receptor tyrosine kinases.
Initially all of them were identified as orphan receptors without known ligands, and their …

In the small intestine, the progeny of stem cells migrate in precise patterns. Absorptive,
enteroendocrine, and goblet cells migrate toward the villus while Paneth cells occupy the …

Eph receptor tyrosine kinases and their cell-surface-bound ligands, the ephrins, regulate
axon guidance and bundling in the developing brain, control cell migration and adhesion …

We report that the many Eph-related receptor tyrosine kinases, and their numerous
membrane-bound ligands, can each be grouped into only two major specificity subclasses …

The term 'vasculogenesis' refers to the earliest stages of vascular development, during
which vascular endothelial cell precursors undergo differentiation, expansion, and …

Ephrin-B2 is a transmembrane ligand that is specifically expressed on arteries but not veins
and that is essential for cardiovascular development. However, ephrin-B2 is also expressed …

The control of cell movement during development is essential for forming and stabilizing the
spatial organization of tissues and cell types. During initial steps of tissue patterning, distinct …

The Eph receptors comprise the largest group of receptor tyrosine kinases and are found in
a wide variety of cell types in developing and mature tissues. Their ligands are the ephrins, a …

The subventricular zone (SVZ) of the lateral ventricles, the largest remaining germinal zone
of the adult mammalian brain, contains an extensive network of neuroblasts migrating …