COVID-19 pandemic presents an unprecedented challenge to identify effective drugs for
treatment. Despite multiple clinical trials using different agents, there is still a lack of specific …

Pathological processes in hematologic diseases originate at the single-cell level, often
making measurements on individual cells more clinically relevant than population averages …

Background: Blood transfusion in the management of severely injured patients can be
lifesaving. These patients are susceptible to developing early coagulopathy, thus …

Traumatic injury to the spinal cord causes permanent loss of function and major personal,
social, and economic problems. Cell-based delivery strategies is a promising approach for …

Abstract Background The species Himatanthus drasticus is popularly known in Northeast
Brazil as" janaguba" and belongs to the family Apocynaceae. The latex collected from its …

Counterproductive lung inflammation and dysregulated thrombosis contribute importantly to
the lethality of advanced COVID-19. Adenosine A2A receptors (A2AR), expressed by a wide …

Loss of intestinal barrier function after burn injury allows movement of intraluminal contents
across the mucosa, which can lead to the development of distant organ injury and multiple …

In recent years, using genetic engineering and bioengineering techniques, Bifidobacterium
as a carrier to express specific functions of the protein or polypeptide, has become a new …

Introduction Transforming growth factor-β1 (TGF-β1) has been implicated in the
pathogenesis of Peyronie's disease (PD) and also plays a role in collagen and elastin …

BACKGROUND: The purpose of this study was to assess acute lung injury when protection
to the gut mucosal barrier offered by vagus nerve stimulation is eliminated by an abdominal …