Exposure to per-and polyfluoroalkyl substances and markers of liver injury: a systematic review and meta-analysis

E Costello, S Rock, N Stratakis, SP Eckel… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Experimental evidence indicates that exposure to certain pollutants is
associated with liver damage. Per-and polyfluoroalkyl substances (PFAS) are persistent …

Per‐and polyfluoroalkyl substance toxicity and human health review: Current state of knowledge and strategies for informing future research

SE Fenton, A Ducatman, A Boobis… - Environmental …, 2021 - Wiley Online Library
Reports of environmental and human health impacts of per‐and polyfluoroalkyl substances
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …

[HTML][HTML] Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease

P Sen, S Qadri, PK Luukkonen, O Ragnarsdottir… - Journal of …, 2022 - Elsevier
Background & aims Recent experimental models and epidemiological studies suggest that
specific environmental contaminants (ECs) contribute to the initiation and pathology of non …

Risk to human health related to the presence of perfluoroalkyl substances in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluoroalkyl substances (PFAS s) in food. Based …

Risk to human health related to the presence of perfluorooctane sulfonic acid and perfluorooctanoic acid in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2018 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluorooctane sulfonic acid (PFOS) and …

[HTML][HTML] Perfluoroalkyl substances and severity of nonalcoholic fatty liver in children: an untargeted metabolomics approach

R Jin, R McConnell, C Catherine, S Xu, DI Walker… - Environment …, 2020 - Elsevier
Background Toxicant-associated steatohepatitis has been described in adults but less is
known regarding the role of toxicants in liver disease of children. Perfluoroalkyl substances …

[HTML][HTML] Evolution of evidence on PFOA and health following the assessments of the C8 Science Panel

K Steenland, T Fletcher, CR Stein, SM Bartell… - Environment …, 2020 - Elsevier
Abstract Background The C8 Science Panel was composed of three epidemiologists
charged with studying the possible health effects of PFOA in a highly exposed population in …

[HTML][HTML] Per-and perfluoroalkyl substances alternatives, mixtures and liver function in adults: A community-based population study in China

JJ Liu, XX Cui, YW Tan, PX Dong, YQ Ou, QQ Li… - Environment …, 2022 - Elsevier
Experimental evidence has shown that per-and polyfluoroalkyl substances (PFAS)
alternatives and mixtures may exert hepatotoxic effects in animals. However …

Environmental perfluoroalkyl acid exposures are associated with liver disease characterized by apoptosis and altered serum adipocytokines

J Bassler, A Ducatman, M Elliott, S Wen… - Environmental …, 2019 - Elsevier
Exposures to perfluoroalkyl substances (PFAS) including perfluoroalkyl acids (PFAAs) are
associated with increased liver enzymes in cohort studies including the C8 Health Study. In …

[HTML][HTML] Effects of environmental contaminants in water resources on nonalcoholic fatty liver disease

S Zheng, Y Yang, C Wen, W Liu, L Cao, X Feng… - Environment …, 2021 - Elsevier
The global prevalence of nonalcoholic fatty liver disease (NAFLD) has been increasing
rapidly in recent years, which is now estimated to be over 25%. NAFLD is one of the most …