Dysfunction of cellular homeostasis can lead to misfolding of proteins thus acquiring
conformations prone to polymerization into pathological aggregates. This process is …

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Background The elderly patients admitted to cardiac intensive care unit (CICU) are at
relatively high risk for developing delirium. A simple and reliable predictive model can …

Trauma represents one of the leading causes of death worldwide. Traumatic injuries elicit a
dynamic inflammatory response with systemic release of inflammatory cytokines. Disbalance …

Trauma-induced coagulopathy (TIC) is a global inflammatory state accompanied by
coagulation derangements, acidemia, and hypothermia, which occurs after traumatic injury …

Background Coagulopathic bleeding is a major cause of mortality after trauma, and platelet
dysfunction contributes to this problem. The causes of platelet dysfunction are relatively …

Abstract Purpose of Review Coagulopathy is a complex pathological condition manifested
through the insufficient or excessive tendency to form blood thrombi, which can be caused …

Acute or chromic bleeding, such as epistaxis, requires hemostatic materials to assist
hemostasis. Even in complex cases, hemostatic materials must have other functions …

Introduction In multiple trauma patients, the occurrence of trauma-induced coagulopathy
(TIC) is closely associated with tissue damage and coagulation function abnormalities in the …

Traumatic brain injury is an outcome of external forces' physical or mechanical impact on the
brain. Thus, the silent epidemic has complex pathophysiology affecting the brain along with …