Biology, vulnerabilities and clinical applications of circulating tumour cells

A Ring, BD Nguyen-Sträuli, A Wicki, N Aceto - Nature Reviews Cancer, 2023 - nature.com
In recent years, exceptional technological advances have enabled the identification and
interrogation of rare circulating tumour cells (CTCs) from blood samples of patients, leading …

Circulating tumour cells for early detection of clinically relevant cancer

R Lawrence, M Watters, CR Davies, K Pantel… - Nature Reviews Clinical …, 2023 - nature.com
Given that cancer mortality is usually a result of late diagnosis, efforts in the field of early
detection are paramount to reducing cancer-related deaths and improving patient outcomes …

A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

[HTML][HTML] Circulating tumor cell technologies

MM Ferreira, VC Ramani, SS Jeffrey - Molecular oncology, 2016 - Elsevier
Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform
the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of …

Challenges in circulating tumour cell research

C Alix-Panabières, K Pantel - Nature Reviews Cancer, 2014 - nature.com
During the past ten years, circulating tumour cells (CTCs) have received enormous attention
as new biomarkers and the subject of basic research. Although CTCs are already used in …

Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells

A Mishra, TD Dubash, JF Edd… - Proceedings of the …, 2020 - National Acad Sciences
Circulating tumor cell (CTC)-based liquid biopsies provide unique opportunities for cancer
diagnostics, treatment selection, and response monitoring, but even with advanced …

[HTML][HTML] Circulating biomarkers for early detection and clinical management of colorectal cancer

M Marcuello, V Vymetalkova, RPL Neves… - Molecular Aspects of …, 2019 - Elsevier
New non-invasive approaches that can complement and improve on current strategies for
colorectal cancer (CRC) screening and management are urgently needed. A growing …

Circulating tumor cells: liquid biopsy of cancer

C Alix-Panabières, K Pantel - Clinical chemistry, 2013 - academic.oup.com
BACKGROUND The detection and molecular characterization of circulating tumor cells
(CTCs) are one of the most active areas of translational cancer research, with> 400 clinical …

Surface modification of stainless steel for biomedical applications: Revisiting a century-old material

A Bekmurzayeva, WJ Duncanson, HS Azevedo… - Materials Science and …, 2018 - Elsevier
Stainless steel (SS) has been widely used as a material for fabricating cardiovascular
stents/valves, orthopedic prosthesis, and other devices and implants used in biomedicine …

Functional analysis of circulating tumour cells: the KEY to understand the biology of the metastatic cascade

Z Eslami-S, LE Cortes-Hernandez, F Thomas… - British Journal of …, 2022 - nature.com
Metastasis formation is the main cause of cancer-related death in patients with solid
tumours. At the beginning of this process, cancer cells escape from the primary tumour to the …