Peptides as multifunctional players in cancer therapy

SMP Vadevoo, S Gurung, HS Lee… - … & Molecular Medicine, 2023 - nature.com
Peptides exhibit lower affinity and a shorter half-life in the body than antibodies. Conversely,
peptides demonstrate higher efficiency in tissue penetration and cell internalization than …

Peptide-based supramolecular hydrogels for local drug delivery

Z Zhang, S Ai, Z Yang, X Li - Advanced Drug Delivery Reviews, 2021 - Elsevier
Peptide-based supramolecular hydrogels have shown great promise as drug delivery
systems (DDSs) because of their excellent biocompatibility, biodegradability, biological …

[HTML][HTML] Current progress, strategy, and prospects of PD-1/PDL-1 immune checkpoint biosensing platforms for cancer diagnostics, therapy monitoring, and drug …

K Ratajczak, H Grel, P Olejnik, S Jakiela… - Biosensors and …, 2023 - Elsevier
Recent technological advancements in testing and monitoring instrumentation have greatly
contributed to the progress in cancer treatment by surgical, chemotherapeutic and …

Enzyme-responsive polymeric micelles of cabazitaxel for prostate cancer targeted therapy

A Barve, A Jain, H Liu, Z Zhao, K Cheng - Acta biomaterialia, 2020 - Elsevier
Cabazitaxel, a novel tubulin inhibitor with poor affinity for P-glycoprotein, is a second-
generation taxane holding great promise for the treatment of metastatic castration-resistant …

[HTML][HTML] Natural peptides for immunological regulation in cancer therapy: mechanism, facts and perspectives

Y Zhang, C Liu, C Wu, L Song - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cancer incidence and mortality rates are increasing annually. Treatment with surgery,
chemotherapy and radiation therapy (RT) is unsatisfactory because many patients have …

[HTML][HTML] Current research status of anti-cancer peptides: Mechanism of action, production, and clinical applications

RK Chinnadurai, N Khan, GK Meghwanshi… - Biomedicine & …, 2023 - Elsevier
The escalating rate of cancer cases, together with treatment deficiencies and long-term side
effects of currently used cancer drugs, has made this disease a global burden of the 21st …

Hydrogel systems for targeted cancer therapy

X Li, X Xu, M Xu, Z Geng, P Ji, Y Liu - Frontiers in Bioengineering and …, 2023 - frontiersin.org
When hydrogel materials with excellent biocompatibility and biodegradability are used as
excellent new drug carriers in the treatment of cancer, they confer the following three …

Liposome-mediated PD-L1 multivalent binding promotes the lysosomal degradation of PD-L1 for T cell-mediated antitumor immunity

S Yang, MK Shim, S Song, H Cho, J Choi, SI Jeon… - Biomaterials, 2022 - Elsevier
Immune checkpoint blockade (ICB) has shown remarkable therapeutic efficacy in a variety of
cancers. However, patients exhibit unexpectedly low response rates to ICB therapy owing to …

Near infrared photoimmunotherapy: a review of recent progress and their target molecules for cancer therapy

TM Mohiuddin, C Zhang, W Sheng, M Al-Rawe… - International journal of …, 2023 - mdpi.com
Near infrared photoimmunotherapy (NIR-PIT) is a newly developed molecular targeted
cancer treatment, which selectively kills cancer cells or immune-regulatory cells and induces …

[HTML][HTML] Immunogenic cell death inducer peptides: A new approach for cancer therapy, current status and future perspectives

H Aria, M Rezaei - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Abstract Immunogenic Cell Death (ICD) is a type of cell death that kills tumor cells by
stimulating the adaptive immune response against other tumor cells. ICD depends on the …