Multivalent glycosystems for human lectins

M Martínez-Bailén, J Rojo… - Chemical Society …, 2023 - pubs.rsc.org
Human lectins are involved in a wide variety of biological processes, both physiological and
pathological, which have attracted the interest of the scientific community working in the …

The sugar code: letters and vocabulary, writers, editors and readers and biosignificance of functional glycan–lectin pairing

H Kaltner, J Abad-Rodríguez, AP Corfield… - Biochemical …, 2019 - portlandpress.com
Ubiquitous occurrence in Nature, abundant presence at strategically important places such
as the cell surface and dynamic shifts in their profile by diverse molecular switches qualifies …

Targeted and equally distributed delivery of mrna to organs with pentaerythritol-based one-component ionizable amphiphilic janus dendrimers

J Lu, EN Atochina-Vasserman, DS Maurya… - Journal of the …, 2023 - ACS Publications
Delivery of nucleic acids with viral and synthetic vectors has pioneered genetic
nanomedicine. Four-component lipid nanoparticles (LNPs) consisting of ionizable lipids …

Chemokines and galectins form heterodimers to modulate inflammation

V Eckardt, MC Miller, X Blanchet, R Duan… - EMBO …, 2020 - embopress.org
Chemokines and galectins are simultaneously upregulated and mediate leukocyte
recruitment during inflammation. Until now, these effector molecules have been considered …

Multivalent glycans for biological and biomedical applications

Y Kim, JY Hyun, I Shin - Chemical Society Reviews, 2021 - pubs.rsc.org
Recognition of glycans by proteins plays a crucial role in a variety of physiological
processes in cells and living organisms. In addition, interactions of glycans with proteins are …

What is the sugar code?

HJ Gabius, M Cudic, T Diercks, H Kaltner… - …, 2022 - Wiley Online Library
A code is defined by the nature of the symbols, which are used to generate information‐
storing combinations (eg oligo‐and polymers). Like nucleic acids and proteins, oligo‐and …

Screening Libraries to Discover Molecular Design Principles for the Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers …

J Lu, EN Atochina-Vasserman, DS Maurya, MI Shalihin… - Pharmaceutics, 2023 - mdpi.com
Viral and synthetic vectors to deliver nucleic acids were key to the rapid development of
extraordinarily efficient COVID-19 vaccines. The four-component lipid nanoparticles (LNPs) …

[PDF][PDF] How galectins have become multifunctional proteins

G García Caballero, H Kaltner, TJ Kutzner, AK Ludwig… - 2020 - hh.um.es
Having identified glycans of cellular glycoconjugates as versatile molecular messages, their
recognition by sugar receptors (lectins) is a fundamental mechanism within the flow of …

Stimuli-responsive principles of supramolecular organizations emerging from self-assembling and self-organizable dendrons, dendrimers, and dendronized polymers

V Percec, D Sahoo, J Adamson - Polymers, 2023 - mdpi.com
All activities of our daily life, of the nature surrounding us and of the entire society and its
complex economic and political systems are affected by stimuli. Therefore, understanding …

[HTML][HTML] Therapeutic potential of targeting galectins–A biomaterials-focused perspective

S Martin-Saldana, MT Chevalier, A Pandit - Biomaterials, 2022 - Elsevier
Among all the biological entities involved in the immune response, galectins, a family of
glycan-binding proteins, have been described as key in immune cell homeostasis and …