Nutritional influences on brain development
MK Georgieff, SE Ramel, SE Cusick - Acta Paediatrica, 2018 - Wiley Online Library
There is increasing evidence from preclinical and human studies that nutrition in the late
foetal and early neonatal period has a significant impact on neurodevelopment across the …
foetal and early neonatal period has a significant impact on neurodevelopment across the …
Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands
Precise deposition of CpG methylation is critical for mammalian development and tissue
homeostasis and is often dysregulated in human diseases. The localization of de novo DNA …
homeostasis and is often dysregulated in human diseases. The localization of de novo DNA …
Analysis and performance assessment of the whole genome bisulfite sequencing data workflow: currently available tools and a practical guide to advance DNA …
DNA methylation is associated with transcriptional repression, genomic imprinting, stem cell
differentiation, embryonic development, and inflammation. Aberrant DNA methylation can …
differentiation, embryonic development, and inflammation. Aberrant DNA methylation can …
Base editor scanning charts the DNMT3A activity landscape
DNA methylation is critical for regulating gene expression, necessitating its accurate
placement by enzymes such as the DNA methyltransferase DNMT3A. Dysregulation of this …
placement by enzymes such as the DNA methyltransferase DNMT3A. Dysregulation of this …
[HTML][HTML] Dysregulation of neuronal genes by fetal-neonatal iron deficiency anemia is associated with altered DNA methylation in the rat hippocampus
YC Lien, DE Condon, MK Georgieff, RA Simmons… - Nutrients, 2019 - mdpi.com
Early-life iron deficiency results in long-term abnormalities in cognitive function and affective
behavior in adulthood. In preclinical models, these effects have been associated with long …
behavior in adulthood. In preclinical models, these effects have been associated with long …
[HTML][HTML] Changes in Phenotypes and DNA Methylation of In Vitro Aging Sperm in Common Carp Cyprinus carpio
The purpose of the current study was to analyze phenotypic and functional characteristics of
common carp (Cyprinus carpio) spermatozoa during in vitro aging and to investigate …
common carp (Cyprinus carpio) spermatozoa during in vitro aging and to investigate …
Grafting‐induced seed gossypol levels by demethylation of (+)‐delta‐cadinene synthase genes in upland cotton
Two‐year‐grafting experiments within and between Gossypium barbadense and Gossypium
hirsutum accessions were conducted to study the source, transfer, and alteration of gossypol …
hirsutum accessions were conducted to study the source, transfer, and alteration of gossypol …
Epigenetic control of ataxin‐1 in multiple sclerosis
Objective ATXN1 encodes the polyglutamine protein ataxin‐1, which we have demonstrated
exerting an immunomodulatory function in the context of central nervous system (CNS) …
exerting an immunomodulatory function in the context of central nervous system (CNS) …
Integrative multi‐omic analysis reveals neurodevelopmental gene dysregulation in CIC‐knockout and IDH1‐mutant cells
SD Lee, J Song, VG LeBlanc… - The Journal of …, 2022 - Wiley Online Library
Capicua (CIC)'s transcriptional repressor function is implicated in neurodevelopment and in
oligodendroglioma (ODG) aetiology. However, CIC's role in these contexts remains obscure …
oligodendroglioma (ODG) aetiology. However, CIC's role in these contexts remains obscure …
[HTML][HTML] Performance of mapping approaches for whole-genome bisulfite sequencing data in crop plants
C Grehl, M Wagner, I Lemnian, B Glaser… - Frontiers in plant …, 2020 - frontiersin.org
DNA methylation is involved in many different biological processes in the development and
well-being of crop plants such as transposon activation, heterosis, environment-dependent …
well-being of crop plants such as transposon activation, heterosis, environment-dependent …