Inflammation and tumor progression: signaling pathways and targeted intervention
H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …
either promotes or suppresses tumor progression, potentially displaying opposing effects on …
Reciprocal regulation of mesenchymal stem cells and immune responses
Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …
Cytokines and chemokines involved in osteoarthritis pathogenesis
Osteoarthritis is a common cause of disability worldwide. Although commonly referred to as
a disease of the joint cartilage, osteoarthritis affects all joint tissues equally. The …
a disease of the joint cartilage, osteoarthritis affects all joint tissues equally. The …
Mesenchymal stem cells for neurological disorders
A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …
Cell membrane-coated mimics: a methodological approach for fabrication, characterization for therapeutic applications, and challenges for clinical translation
V Chugh, K Vijaya Krishna, A Pandit - ACS nano, 2021 - ACS Publications
Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell
membrane and a template of choice to mimic the functions of a cell. The design exploits its …
membrane and a template of choice to mimic the functions of a cell. The design exploits its …
Potential pre-activation strategies for improving therapeutic efficacy of mesenchymal stem cells: current status and future prospects
M Li, Y Jiang, Q Hou, Y Zhao, L Zhong, X Fu - Stem cell research & …, 2022 - Springer
Mesenchymal stem cell (MSC)-based therapy has been considered as a promising
approach targeting a variety of intractable diseases due to remarkable multiple effect of …
approach targeting a variety of intractable diseases due to remarkable multiple effect of …
[HTML][HTML] Homing and migration of mesenchymal stromal cells: how to improve the efficacy of cell therapy?
A De Becker, I Van Riet - World journal of stem cells, 2016 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSCs) are currently being investigated for use in a wide variety
of clinical applications. For most of these applications, systemic delivery of the cells is …
of clinical applications. For most of these applications, systemic delivery of the cells is …
Hypoxia-responsive nanoparticle based drug delivery systems in cancer therapy: an up-to-date review
R Kumari, D Sunil, RS Ningthoujam - Journal of Controlled Release, 2020 - Elsevier
Hypoxia is a salient feature observed in most solid malignancies that holds a pivotal role in
angiogenesis, metastasis and resistance to conventional cancer therapeutic approaches …
angiogenesis, metastasis and resistance to conventional cancer therapeutic approaches …
Genetically engineered and enucleated human mesenchymal stromal cells for the targeted delivery of therapeutics to diseased tissue
H Wang, CN Alarcón, B Liu, F Watson… - Nature biomedical …, 2022 - nature.com
Targeting the delivery of therapeutics specifically to diseased tissue enhances their efficacy
and decreases their side effects. Here we show that mesenchymal stromal cells with their …
and decreases their side effects. Here we show that mesenchymal stromal cells with their …
Mesenchymal stem cells for chronic wound healing: current status of preclinical and clinical studies
YZ Huang, M Gou, LC Da, WQ Zhang… - Tissue Engineering Part …, 2020 - liebertpub.com
Healing skin wounds with anatomic and functional integrity, especially under chronic
pathological conditions, remain an enormous challenge. Due to their outstanding …
pathological conditions, remain an enormous challenge. Due to their outstanding …