Gliomas are the most common central nervous system tumors. New technologies, including
genetic research and advanced statistical methods, revolutionize the therapeutic approach …

Diffuse gliomas are among the most common adult central nervous system tumors with an
annual incidence of more than 16,000 cases in the United States. Until very recently, the …

Abstract N6-methyladenosine (m 6 A) RNA methylation, associated with cancer initiation
and progression, is dynamically regulated by the m 6 A RNA methylation regulators …

Background: Epithelial-mesenchymal transition (EMT) is regulated by induction factors,
transcription factor families and an array of signaling pathways genes, and has been …

Purpose: In a post hoc analysis of the CATNON trial (NCT00626990), we explored whether
adding temozolomide to radiotherapy improves outcome in patients with IDH1/2 wildtype …

Abstract The 2016 and 2021 World Health Organization 2021 Classification of central
nervous system tumors have resulted in a major improvement in the classification of …

Motivation Many studies have shown that IDH mutation and 1p/19q co-deletion can serve as
prognostic signatures of glioma. Although these genetic variations affect the expression of …

At the time of their clinical manifestation, the heterogeneous group of adult and pediatric
gliomas carries a wide range of diverse somatic genomic alterations, ranging from somatic …

Glioma is the most common and fatal tumor of the central nervous system in humans.
Despite advances in surgery, radiotherapy, and chemotherapeutic agents, glioma still has a …

Background Recent studies have proposed several gene signatures as biomarkers for
different grades of gliomas from various perspectives. However, most of these genes can …