Biochemical and physicochemical characteristics of the major muscle proteins from fish and shellfish
Y Ochiai, H Ozawa - Fisheries science, 2020 - Springer
Fish and marine invertebrates constitute an important part of the human diet worldwide, and
their muscles are the major edible parts. The muscles are a rich source of proteins, which in …
their muscles are the major edible parts. The muscles are a rich source of proteins, which in …
New insights into the regulation of the actin cytoskeleton by tropomyosin
CLA Wang, LM Coluccio - International review of cell and molecular …, 2010 - Elsevier
The actin cytoskeleton is regulated by a variety of actin-binding proteins including those
constituting the tropomyosin family. Tropomyosins are coiled-coil dimers that bind along the …
constituting the tropomyosin family. Tropomyosins are coiled-coil dimers that bind along the …
A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells
The actin cytoskeleton is a potentially vulnerable property of cancer cells, yet
chemotherapeutic targeting attempts have been hampered by unacceptable toxicity. In this …
chemotherapeutic targeting attempts have been hampered by unacceptable toxicity. In this …
Tropomyosin position on F-actin revealed by EM reconstruction and computational chemistry
Electron microscopy and fiber diffraction studies of reconstituted F-actin-tropomyosin
filaments reveal the azimuthal position of end-to-end linked tropomyosin molecules on the …
filaments reveal the azimuthal position of end-to-end linked tropomyosin molecules on the …
Cryo-EM and molecular docking shows myosin loop 4 contacts actin and tropomyosin on thin filaments
The motor protein myosin drives muscle and nonmuscle motility by binding to and moving
along actin of thin filaments. Myosin binding to actin also modulates interactions of the …
along actin of thin filaments. Myosin binding to actin also modulates interactions of the …
Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation
LR Sewanan, J Park, MJ Rynkiewicz… - Journal of General …, 2021 - rupress.org
Hypertrophic cardiomyopathy (HCM) is an inherited disorder caused primarily by mutations
to thick and thinfilament proteins. Although thin filament mutations are less prevalent than …
to thick and thinfilament proteins. Although thin filament mutations are less prevalent than …
Distinct actin–tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes
T Reindl, S Giese, JN Greve, PY Reinke, I Chizhov… - IScience, 2022 - cell.com
The effects of N-terminal acetylation of the high molecular weight tropomyosin isoforms
Tpm1. 6 and Tpm2. 1 and the low molecular weight isoforms Tpm1. 12, Tpm3. 1, and Tpm4 …
Tpm1. 6 and Tpm2. 1 and the low molecular weight isoforms Tpm1. 12, Tpm3. 1, and Tpm4 …
Condensin Smc2-Smc4 dimers are flexible and dynamic
JM Eeftens, AJ Katan, M Kschonsak, M Hassler… - Cell reports, 2016 - cell.com
Structural maintenance of chromosomes (SMC) protein complexes, including cohesin and
condensin, play key roles in the regulation of higher-order chromosome organization. Even …
condensin, play key roles in the regulation of higher-order chromosome organization. Even …
A model of calcium activation of the cardiac thin filament
The cardiac thin filament regulates actomyosin interactions through calcium-dependent
alterations in the dynamics of cardiac troponin and tropomyosin. Over the past several …
alterations in the dynamics of cardiac troponin and tropomyosin. Over the past several …
The relationship between curvature, flexibility and persistence length in the tropomyosin coiled-coil
XE Li, W Lehman, S Fischer - Journal of structural biology, 2010 - Elsevier
The inherent flexibility of rod-like tropomyosin coiled-coils is a significant factor that
constrains tropomyosin's complex positional dynamics on actin filaments. Flexibility of …
constrains tropomyosin's complex positional dynamics on actin filaments. Flexibility of …