[HTML][HTML] Cancer immunotherapy: Pros, cons and beyond

S Tan, D Li, X Zhu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Cancer immunotherapy is an innovative treatment for tumors today. In various experiments
and clinical studies, it has been found that immunotherapy does have incomparable …

Targets of immune escape mechanisms in cancer: basis for development and evolution of cancer immune checkpoint inhibitors

S Dutta, A Ganguly, K Chatterjee, S Spada… - Biology, 2023 - mdpi.com
Simple Summary The tumor immune escape mechanisms are key factors in cancer
progression and metastasis. They are an undeniable hurdle for successful cancer treatment …

Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma

N Auslander, G Zhang, JS Lee, DT Frederick, B Miao… - Nature medicine, 2018 - nature.com
Immune checkpoint blockade (ICB) therapy provides remarkable clinical gains and has
been very successful in treatment of melanoma. However, only a subset of patients with …

Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma

D Miao, CA Margolis, W Gao, MH Voss, W Li… - Science, 2018 - science.org
Immune checkpoint inhibitors targeting the programmed cell death 1 receptor (PD-1)
improve survival in a subset of patients with clear cell renal cell carcinoma (ccRCC). To …

Immunology and immunotherapy of head and neck cancer

RL Ferris - Journal of clinical oncology, 2015 - ascopubs.org
The immune system plays a key role in the development, establishment, and progression of
head and neck squamous cell carcinoma (HNSCC). A greater understanding of the …

Development of PD-1/PD-L1 pathway in tumor immune microenvironment and treatment for non-small cell lung cancer

J He, Y Hu, M Hu, B Li - Scientific reports, 2015 - nature.com
Lung cancer is currently the leading cause of cancer-related death in worldwide, non-small
cell lung cancer (NSCLC) accounts for about 85% of all lung cancers. Surgery, platinum …

[HTML][HTML] Targeted therapies in breast cancer: New challenges to fight against resistance

V Masoud, G Pagès - World journal of clinical oncology, 2017 - ncbi.nlm.nih.gov
Breast cancer is the most common type of cancer found in women and today represents a
significant challenge to public health. With the latest breakthroughs in molecular biology and …

Molecular basis and rationale for combining immune checkpoint inhibitors with chemotherapy in non-small cell lung cancer

A Leonetti, B Wever, G Mazzaschi, YG Assaraf… - Drug Resistance …, 2019 - Elsevier
Immunotherapy has prompted a paradigm shift in advanced non-small cell lung cancer
(NSCLC) treatment, by demonstrating superior efficacy to chemotherapy alone both in …

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

DN Rodrigues, P Rescigno, D Liu… - The Journal of …, 2018 - Am Soc Clin Investig
BACKGROUND. Understanding the integrated immunogenomic landscape of advanced
prostate cancer (APC) could impact stratified treatment selection. METHODS. Defective …

Immunomodulatory potential of natural products from herbal medicines as immune checkpoints inhibitors: Helping to fight against cancer via multiple targets

Z Zhong, CT Vong, F Chen, H Tan… - Medicinal Research …, 2022 - Wiley Online Library
Immunotherapy sheds new light to cancer treatment and is satisfied by cancer patients.
However, immunotoxicity, single‐source antibodies, and single‐targeting stratege are …