Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions

JB Calixto, CAL Kassuya, E André, J Ferreira - Pharmacology & …, 2005 - Elsevier
Members of the transient receptor potential (TRP) family of nonselective cation channels are
involved in several pathological and physiological conditions. The search for the molecular …

Herbal compounds and toxins modulating TRP channels

R Vennekens, J Vriens, B Nilius - Current neuropharmacology, 2008 - ingentaconnect.com
Although the benefits are sometimes obvious, traditional or herbal medicine is regarded with
skepticism, because the mechanism through which plant compounds exert their powers are …

Synthesis and κ-opioid receptor activity of furan-substituted salvinorin A analogues

AP Riley, CE Groer, D Young, AW Ewald… - Journal of medicinal …, 2014 - ACS Publications
The neoclerodane diterpene salvinorin A, found in the leaves of Salvia divinorum, is a potent
κ-opioid receptor agonist, making it an attractive scaffold for development into a treatment for …

Schinus terebinthifolius Raddi: chemical composition, biological properties and toxicity

MG Carvalho, AGN Melo, CFS Aragão… - Revista Brasileira de …, 2013 - SciELO Brasil
Schinus terebinthifolius Raddi is a medicinal plant known in Brazil as" aroeira da praia",
which has been used in popular medicine as antipyretic, analgesic, depurative and in the …

Chemical Profiles and Pharmacological Properties with in Silico Studies on Elatostema papillosum Wedd

MZ Uddin, A Paul, A Rakib, SA Sami, S Mahmud… - Molecules, 2021 - mdpi.com
The current study attempted, for the first time, to qualitatively and quantitatively determine the
phytochemical components of Elatostema papillosum methanol extract and their biological …

[HTML][HTML] Acute toxicity (lethal dose 50 calculation) of herbal drug somina in rats and mice

M Ahmed - Pharmacology & Pharmacy, 2015 - scirp.org
Somina (herbal preparation) prepared by Hamdard Laboratories (Waqf) Pakistan is a
mixture of five different medicinal plants, widely prescribed for the treatment of mental …

[HTML][HTML] Antinociceptive effect of essential oils and their constituents: an update review

EJ Lenardão, L Savegnago, RG Jacob… - Journal of the Brazilian …, 2016 - SciELO Brasil
Plants and essential oils (EOs) have been used for centuries in folk medicine to treat diverse
disorders, including analgesic to pain relief. In this context, the antinociceptive activity of EOs …

Anti-allodynic action of the tormentic acid, a triterpene isolated from plant, against neuropathic and inflammatory persistent pain in mice

LB Bortalanza, J Ferreira, SC Hess… - European journal of …, 2002 - Elsevier
Experiments were designed to address whether the pentacyclic triterpene tormentic acid
isolated from the stem bark of the plant Vochysia divergens exerts oral anti-allodynic …

[HTML][HTML] Evaluation of the antinociceptive, anti-inflammatory and gastric antiulcer activities of the essential oil from Piper aleyreanum C. DC in rodents

DKS Lima, LJ Ballico, FR Lapa, HP Gonçalves… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Piper aleyreanum is a small tree that is widely
distributed in tropical and subtropical regions, mostly in North and South America, and is …

Datura stramonium (Solanaceae): Antioxidant and Antimicrobial Potentials

FS Mohammed, E Kına, M Sevindik… - Turkish Journal of …, 2021 - agrifoodscience.com
Many people in different parts of the world benefit from alternative medicine in the treatment
and prevention of diseases. Plants are among the important natural materials used in …