Many questions have been posed about acquired immunodeficiency syndrome (AIDS)
pathogenesis. Is human immunodeficiency virus (HIV) both necessary and sufficient to …

The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …

▪ Abstract Microglia are the principal immune cells in the central nervous system (CNS) and
have a critical role in host defense against invading microorganisms and neoplastic cells …

HIV virus particles interact with several receptors on cell surfaces. Two receptors, CD4 and a
co-receptor act sequentially to trigger fusion of viral and cellular membranes and confer …

The blood-brain barrier (BBB) is a diffusion barrier that has an important role in maintaining
a precisely regulated microenvironment protecting the neural tissue from infectious agents …

Infection with the human immunodeficiency virus (HIV) is associated with a syndrome of
cognitive and motor abnormalities that may develop in the absence of opportunistic …

Lentiviruses are a subfamily of retroviruses that are characterized by long incubation periods
between infection of the host and the manifestation of clinical disease. Human …

Human immunodeficiency virus type 1 (HIV‐1) infection of the central nervous system is
associated with characteristic virological, clinical, and neuropathological findings in adults …

Entry of human immunodeficiency virus type 1 (HIV-1) requires CD4 and one of a family of
related seven-transmembrane-domain coreceptors. Macrophage-tropic HIV-1 isolates are …

ABSTRACT AIDS dementia and encephalitis are complications of AIDS occurring most
frequently in patients who are immunosuppressed. The simian immunodeficiency virus (SIV) …