Cell spheroids as a versatile research platform: formation mechanisms, high throughput production, characterization and applications

MC Decarli, R Amaral, DP Dos Santos, LB Tofani… - …, 2021 - iopscience.iop.org
Abstract Three-dimensional (3D) cell culture has tremendous advantages to closely mimic
the in vivo architecture and microenvironment of healthy tissue and organs, as well as of …

Confined multiphase swirled flows in chemical engineering

AO Kuzmin - Reviews in Chemical Engineering, 2021 - degruyter.com
Exploration of confined swirled flows in the former USSR and present-day Russia has a long
history and is presented by numerous publications, mostly written in Russian. The obtained …

Modelling of turbulent shear controllable co-precipitation synthesis of lithium ion battery cathode precursor micro-particles in a Taylor-Couette flow reactor with …

L Liu, X Yang, J Yang, G Li, Y Guo, C Xue - Chemical Engineering Journal, 2021 - Elsevier
Turbulent shear controllable co-precipitation synthesis of lithium ion battery cathode
precursor micro-particles, Ni 0.6 Co 0.2 Mn 0.2 (OH) 2 (NCM622), in a Taylor-Couette flow …

Hollow microcarriers for large‐scale expansion of anchorage‐dependent cells in a stirred bioreactor

A YekrangSafakar, A Acun, JW Choi… - Biotechnology and …, 2018 - Wiley Online Library
With recent advances in biotechnology, mammalian cells are used in biopharmaceutical
industries to produce valuable protein therapeutics and investigated as effective therapeutic …

Expansion of Chinese hamster ovary cells via a loose cluster-assisted suspension culture using cell-sized gelatin microcarriers

Y Hasebe, M Yamada, R Utoh, M Seki - Journal of bioscience and …, 2023 - Elsevier
Technologies for efficiently expanding Chinese hamster ovary (CHO) cells, the primary host
cells for antibody production, are of growing industrial importance. Various processes for the …

Feasibility of the taylor vortex flow bioreactor for mesenchymal stromal cell expansion on microcarriers

LVG Gil, H Singh, JS da Silva, DP dos Santos… - Biochemical …, 2020 - Elsevier
It is expected that a high cell volumetric concentration of human mesenchymal stromal cells
(hMSCs) for cell therapy can be achieved by using scalable cell culture platforms as …

Effect of hydrodynamic heterogeneity on micromixing intensification in a Taylor–Couette flow reactor with variable configurations of inner cylinder

L Liu, X Yang, J Yang, G Li, Y Guo - AIChE Journal, 2021 - Wiley Online Library
Abstract Effect of hydrodynamic heterogeneity on micromixing intensification in a Taylor–
Couette flow (TC) reactor with variable configurations of inner cylinder has been …

Experimental and computational studies of oxygen transport in a Taylor-Couette bioreactor

J Qiao, WC Yan, JH Teoh, YW Tong… - Chemical Engineering …, 2018 - Elsevier
With research and development for almost one century, the Taylor-Couette device is now
applied in many practical applications such as reaction, filtration, extraction and bioreactor …

Particle motion in a Taylor vortex

J Qiao, R Deng, CH Wang - International Journal of Multiphase Flow, 2015 - Elsevier
Here we present a study on the behavior of individual particles in the Taylor vortex. Two
particle-fluid systems were tested: a cube with the edge length of 2 mm and the density of …

A large thermal turbulent Taylor-Couette (THETACO) facility for investigation of turbulence induced by simultaneous action of rotation and radial temperature gradient

H Singh, A Bonnesoeur, H Besnard… - Review of Scientific …, 2019 - pubs.aip.org
A thermal turbulent Taylor-Couette facility has been designed to investigate turbulent flows
generated by differential rotation and radial temperature gradient. It consists of a cylindrical …