Background Severe bleeding and coagulopathy are serious clinical conditions that are
associated with high mortality. Thromboelastography (TEG) and thromboelastometry …

Fibrinogen plays several key roles in the maintenance of hemostasis. Its cleavage by
thrombin and subsequent polymerization to form fibrin strands provides the structural …

Objective: To identify an appropriate diagnostic tool for the early diagnosis of acute traumatic
coagulopathy and validate this modality through prediction of transfusion requirements in …

Introduction The appropriate strategy for trauma-induced coagulopathy management is
under debate. We report the treatment of major trauma using mainly coagulation factor …

Objective: To determine the effect of blood component ratios in massive transfusion (MT), we
hypothesized that increased use of plasma and platelet to red blood cell (RBC) ratios would …

Severe trauma-related bleeding is associated with high mortality. Standard coagulation tests
provide limited information on the underlying coagulation disorder. Whole-blood viscoelastic …

Objective To determine the effectiveness of blood component therapy in the correction of
trauma-induced coagulopathy during hemorrhage. Background Severe hemorrhage …

Background To test whether an acute transfusion practice of packed red blood cells (pRBC):
fresh‐frozen plasma (FFP) 1: 1 would be associated with reduced mortality in acute bleeding …

Trauma patients with haemorrhagic shock who only transiently respond or do not respond to
fluid therapy and/or the administration of blood products have exsanguinating injuries …

Objective: The objective of this study was to determine the optimal use of fresh-frozen
plasma (FFP) in trauma. Our hypothesis was that a higher FFP: packed red blood cells …