Deep brain stimulation (DBS) has become the treatment of choice for advanced stages of
Parkinson's disease, medically intractable essential tremor, and complicated segmental and …

High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN-HFS) is the
preferred surgical treatment for advanced Parkinson's disease. In the 15 years since its …

Arrest of ongoing movements is an integral part of executing motor programs. Behavioral
arrest may happen upon termination of a variety of goal-directed movements or as a global …

Deep brain stimulation (DBS) is an established procedure for the symptomatic treatment of
Parkinson's disease. Several deep brain nuclei have been stimulated, producing a wide …

Deep brain stimulation (DBS) has shown remarkable therapeutic benefits for patients with
otherwise treatment-resistant movement and affective disorders. This technique is not only …

Axial motor signs—including gait impairment, postural instability and postural abnormalities—
are common and debilitating symptoms in patients with advanced Parkinson disease …

Pedunculopontine nucleus region deep brain stimulation (DBS) is a promising but
experimental therapy for axial motor deficits in Parkinson's disease (PD), particularly gait …

The motor signs of Parkinson's disease are thought to result in large part from a reduction of
the level of dopamine in the basal ganglia. Over the last few years, many of the functional …

Gait disturbances and akinesia are extremely disabling in advanced Parkinson's disease. It
has been suggested that modulation of the activity of the pedunculopontine nucleus (PPN) …

The mesencephalic locomotor region (MLR) has been initially identified as a supraspinal
center capable of initiating and modulating locomotion. Whereas its functional contribution to …