Current state of molecular and metabolic strategies for the improvement of L-asparaginase expression in heterologous systems
Heterologous expression of L-asparaginase (L-ASNase) has become an important area of
research due to its clinical and food industry applications. This review provides a …
research due to its clinical and food industry applications. This review provides a …
Heterologous expression of fungal L-asparaginase: a systematic review
KC Rodrigues Andrade, JA Cordeiro de Abreu… - Future …, 2024 - Taylor & Francis
Aim: To review the available literature about heterologous expression of fungal L-
asparaginase (L-ASNase). Materials & methods: A search was conducted across PubMed …
asparaginase (L-ASNase). Materials & methods: A search was conducted across PubMed …
Homology modeling and molecular docking studies to decrease glutamine affinity of Yarrowia lipolytica L-asparaginase
F Darvishi, E Beiranvand, H Kalhor, B Shahbazi… - International Journal of …, 2024 - Elsevier
L-Asparaginase is a key component in the treatment of leukemias and lymphomas.
However, the glutamine affinity of this therapeutic enzyme is an off-target activity that causes …
However, the glutamine affinity of this therapeutic enzyme is an off-target activity that causes …
A Structural In Silico Analysis of the Immunogenicity of L-Asparaginase from Penicillium cerradense
KCR Andrade, M Homem-de-Mello, JA Motta… - International Journal of …, 2024 - mdpi.com
L-asparaginase is an essential drug used to treat acute lymphoid leukemia (ALL), a cancer
of high prevalence in children. Several adverse reactions associated with L-asparaginase …
of high prevalence in children. Several adverse reactions associated with L-asparaginase …
l-Asparaginase Type II from Fusarium proliferatum: Heterologous Expression and In Silico Analysis
SL Cardoso, PM Souza, K Rodrigues, IS Mota, EF Filho… - Pharmaceutics, 2023 - mdpi.com
The search for new drug-producing microorganisms is one of the most promising situations
in current world scientific scenarios. The use of molecular biology as well as the cloning of …
in current world scientific scenarios. The use of molecular biology as well as the cloning of …
MICROBIAL L-ASPARAGINASES AND STRATEGIES TO IMPROVE THEM
D Achnafani, AN Sari - Jurnal Bioteknologi dan Biosains …, 2023 - ejournal.brin.go.id
L-asparaginase is a type of hydrolase enzyme that has been used in anticancer treatment,
mainly Acute Lymphoblastic Leukemia (ALL). L-asparaginase reduces the blood supply of L …
mainly Acute Lymphoblastic Leukemia (ALL). L-asparaginase reduces the blood supply of L …
[PDF][PDF] ПОДХОДЫ ДЛЯ УЛУЧШЕНИЯ ЭКСПРЕССИИ L-АСПАРАГИНАЗЫ В ГЕТЕРОЛОГИЧНЫХ СИСТЕМАХ
ЮА Гладилина, АН Шишпарёнок… - Биомедицинская …, 2023 - scholar.archive.org
L-аспарагиназа (КФ 3.5. 1.1) является одним из самых востребованных ферментов,
который используется в медицине в качестве лекарственного средства, а в пищевой …
который используется в медицине в качестве лекарственного средства, а в пищевой …