Feature fusion-based food protein subcellular prediction for drug composition

H Byeon, M Shabaz, JVN Ramesh, AK Dutta, R Vijay… - Food Chemistry, 2024 - Elsevier
The structure and function of dietary proteins, as well as their subcellular prediction, are
critical for designing and developing new drug compositions and understanding the …

Applications of deep learning for drug discovery systems with bigdata

Y Matsuzaka, R Yashiro - BioMedInformatics, 2022 - mdpi.com
The adoption of “artificial intelligence (AI) in drug discovery”, where AI is used in the process
of pharmaceutical research and development, is progressing. By using the ability to process …

PScL-HDeep: image-based prediction of protein subcellular location in human tissue using ensemble learning of handcrafted and deep learned features with two …

M Ullah, K Han, F Hadi, J Xu, J Song… - Briefings in …, 2021 - academic.oup.com
Protein subcellular localization plays a crucial role in characterizing the function of proteins
and understanding various cellular processes. Therefore, accurate identification of protein …

Multi-scale deep learning for the imbalanced multi-label protein subcellular localization prediction based on immunohistochemistry images

F Wang, L Wei - Bioinformatics, 2022 - academic.oup.com
Motivation The development of microscopic imaging techniques enables us to study protein
subcellular locations from the tissue level down to the cell level, contributing to the rapid …

Integrative survival analysis of breast cancer with gene expression and DNA methylation data

I Bichindaritz, G Liu, C Bartlett - Bioinformatics, 2021 - academic.oup.com
Motivation Integrative multi-feature fusion analysis on biomedical data has gained much
attention recently. In breast cancer, existing studies have demonstrated that combining …

DLMBHCO: design of an augmented bioinspired deep learning-based multidomain body parameter analysis via heterogeneous correlative body organ analysis

SN Ajani, RA Mulla, S Limkar, R Ashtagi, SK Wagh… - Soft Computing, 2023 - Springer
Progressive organ-level disorders in the human body are often correlated with diseases in
other body parts. For instance, liver diseases can be linked with heart issues, while cancers …

Automated classification of protein subcellular localization in immunohistochemistry images to reveal biomarkers in colon cancer

ZZ Xue, Y Wu, QZ Gao, L Zhao, YY Xu - BMC bioinformatics, 2020 - Springer
Background Protein biomarkers play important roles in cancer diagnosis. Many efforts have
been made on measuring abnormal expression intensity in biological samples to identity …

A Review for Artificial Intelligence Based Protein Subcellular Localization

H Xiao, Y Zou, J Wang, S Wan - Biomolecules, 2024 - mdpi.com
Proteins need to be located in appropriate spatiotemporal contexts to carry out their diverse
biological functions. Mislocalized proteins may lead to a broad range of diseases, such as …

MiRLoc: predicting miRNA subcellular localization by incorporating miRNA–mRNA interactions and mRNA subcellular localization

M Xu, Y Chen, Z Xu, L Zhang, H Jiang… - Briefings in …, 2022 - academic.oup.com
Subcellular localization of microRNAs (miRNAs) is an important reflection of their biological
functions. Considering the spatio-temporal specificity of miRNA subcellular localization …

Dual-Signal Feature Spaces Map Protein Subcellular Locations Based on Immunohistochemistry Image and Protein Sequence

K Zou, S Wang, Z Wang, H Zou, F Yang - Sensors, 2023 - mdpi.com
Protein is one of the primary biochemical macromolecular regulators in the compartmental
cellular structure, and the subcellular locations of proteins can therefore provide information …