Sex determination, gonadal sex differentiation, and plasticity in vertebrate species

Y Nagahama, T Chakraborty… - Physiological …, 2021 - journals.physiology.org
A diverse array of sex determination (SD) mechanisms, encompassing environmental to
genetic, have been found to exist among vertebrates, covering a spectrum from fixed SD …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Endocrine disruptors and obesity

PD Darbre - Current obesity reports, 2017 - Springer
Abstract Purpose of Review The purpose of this review was to summarise current evidence
that some environmental chemicals may be able to interfere in the endocrine regulation of …

Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects

BS Rubin - The Journal of steroid biochemistry and molecular …, 2011 - Elsevier
Bisphenol A (BPA) is one of the highest volume chemicals produced worldwide. This
compound is a building block of polycarbonate plastics often used for food and beverage …

Endocrine disrupting chemicals and disease susceptibility

TT Schug, A Janesick, B Blumberg… - The Journal of steroid …, 2011 - Elsevier
Environmental chemicals have significant impacts on biological systems. Chemical
exposures during early stages of development can disrupt normal patterns of development …

Developmental origins of health and disease: a paradigm for understanding disease cause and prevention

JJ Heindel, LN Vandenberg - Current opinion in pediatrics, 2015 - journals.lww.com
The evidence in support of the developmental origins of the health and disease paradigm is
sufficiently robust and repeatable across species, including humans, to suggest a need for …

Endocrine-disrupting chemicals: an Endocrine Society scientific statement

E Diamanti-Kandarakis, JP Bourguignon… - Endocrine …, 2009 - academic.oup.com
There is growing interest in the possible health threat posed by endocrine-disrupting
chemicals (EDCs), which are substances in our environment, food, and consumer products …

Transgenerational epigenetic inheritance: prevalence, mechanisms, and implications for the study of heredity and evolution

E Jablonka, G Raz - The Quarterly review of biology, 2009 - journals.uchicago.edu
This review describes new developments in the study of transgenerational epigenetic
inheritance, a component of epigenetics. We start by examining the basic concepts of the …

Environmental epigenomics and disease susceptibility

RL Jirtle, MK Skinner - Nature reviews genetics, 2007 - nature.com
Epidemiological evidence increasingly suggests that environmental exposures early in
development have a role in susceptibility to disease in later life. In addition, some of these …