Experimental embryology of gastrulation: pluripotent stem cells as a new model system

N Moris, AM Arias, B Steventon - Current opinion in genetics & …, 2020 - Elsevier
Gastrulation is an inherently complicated process involving a well-orchestrated series of
collective cellular behaviours that lead to the emergence of the body plan of the organism. A …

Studying evolution of the primary body axis in vivo and in vitro

K Anlas, V Trivedi - Elife, 2021 - elifesciences.org
The metazoan body plan is established during early embryogenesis via collective cell
rearrangements and evolutionarily conserved gene networks, as part of a process …

Zebrafish embryonic explants undergo genetically encoded self-assembly

A Schauer, D Pinheiro, R Hauschild, CP Heisenberg - Elife, 2020 - elifesciences.org
Embryonic stem cell cultures are thought to self-organize into embryoid bodies, able to
undergo symmetry-breaking, germ layer specification and even morphogenesis. Yet, it is …

Nodal and planar cell polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements

MLK Williams, L Solnica-Krezel - Elife, 2020 - elifesciences.org
During vertebrate gastrulation, convergence and extension (C and E) of the primary
anteroposterior (AP) embryonic axis is driven by polarized mediolateral (ML) cell …

Axial elongation of caudalized human organoids mimics neural tube development

ARG Libby, DA Joy, NH Elder, EA Bulger, MZ Krakora… - BioRxiv, 2020 - biorxiv.org
During mammalian embryogenesis, axial elongation of the neural tube is critical for
establishing the anterior-posterior body axis, but is difficult to interrogate directly because it …

[PDF][PDF] β-Catenin and canonical Wnts control two separate pattern formation systems in Hydra: Insights from mathematical modelling

M Mercker, T Lengfeld, S Höger, A Tursch, M Lommel… - BioRxiv, 2021 - researchgate.net
Formation of the body axes and the subsequent formation of the apical termini are two
fundamental steps during animal development. In Hydra, nuclear β-Catenin and canonical …

Studying evolution of the primary body axis in vivo and in vitro

A Kerim, T Vikas - eLife, 2021 - search.proquest.com
The metazoan body plan is established during early embryogenesis via collective cell
rearrangements and evolutionarily conserved gene networks, as part of a process …

linus: Conveniently explore, share, and present large-scale biological trajectory data in a web browser

J Waschke, M Hlawitschka, K Anlas… - PLoS computational …, 2021 - journals.plos.org
In biology, we are often confronted with information-rich, large-scale trajectory data, but
exploring and communicating patterns in such data can be a cumbersome task. Ideally, the …

β-catenin and canonical Wnts in Hydra pattern formation: Insights from mathematical modelling into two distinct systems

M Mercker, A Kazarnikov, A Tursch, S Höger… - bioRxiv, 2021 - biorxiv.org
Formation of the body axes and the subsequent formation of the apical termini are
fundamental steps during animal development. Nuclear β-catenin and canonical Wnt3 have …

[PDF][PDF] Two separate but interconnected pattern formation systems are required to control body-axis and head-organiser formation in Hydra

M Mercker, A Tursch, F Veerman, A Kazarnikov… - biorxiv.org
Understanding the mechanisms responsible for formation of the primary body axis is a
crucial issue in developmental biology 14 (65). The process can be based on maternally …