[HTML][HTML] Neuroinflammation in Parkinson's disease: from gene to clinic: a systematic review

C Castillo-Rangel, G Marin… - International Journal of …, 2023 - mdpi.com
Parkinson's disease is a neurodegenerative disease whose progression and clinical
characteristics have a close bidirectional and multilevel relationship with the process of …

[HTML][HTML] Anxiety in synucleinopathies: neuronal circuitry, underlying pathomechanisms and current therapeutic strategies

TT Lai, B Gericke, M Feja, M Conoscenti… - npj Parkinson's …, 2023 - nature.com
Synucleinopathies are neurodegenerative disorders characterized by alpha-synuclein
(αSyn) accumulation in neurons or glial cells, including Parkinson's disease (PD), dementia …

Extracellular vesicle biomarkers for cognitive impairment in Parkinson's disease

J Blommer, T Pitcher, M Mustapic, E Eren, PJ Yao… - Brain, 2023 - academic.oup.com
Besides motor symptoms, many individuals with Parkinson's disease develop cognitive
impairment perhaps due to coexisting α-synuclein and Alzheimer's disease pathologies and …

[HTML][HTML] Identifying key multi-modal predictors of incipient dementia in Parkinson's disease: a machine learning analysis and Tree SHAP interpretation

GP McFall, L Bohn, M Gee, SM Drouin… - Frontiers in Aging …, 2023 - frontiersin.org
Background Persons with Parkinson's disease (PD) differentially progress to cognitive
impairment and dementia. With a 3-year longitudinal sample of initially non-demented PD …

[HTML][HTML] Anxiety, depression, and apathy as predictors of cognitive decline in patients with Parkinson's disease—a three-year follow-up study

K Toloraia, A Meyer, S Beltrani, P Fuhr, R Lieb… - Frontiers in …, 2022 - frontiersin.org
Objective Anxiety, depression, and apathy are the most common neuropsychiatric symptoms
in Parkinson's disease (PD) patients. They impair cognitive functioning and have a profound …

[HTML][HTML] Prevalence, treatment, and neural correlates of apathy in different forms of dementia: a narrative review

I Parrotta, S Cacciatore, F D'Andrea, M D'Anna… - Neurological …, 2024 - Springer
Objectives The aim of this review is to provide an overview on prevalence and clinical tools
for the diagnosis of apathy, as well as on neurophysiological and neuroimaging findings …

Risk of Dementia in Parkinson's Disease: A Systematic Review and Meta‐Analysis

LL Gibson, D Weintraub, R Lemmen… - Movement …, 2024 - Wiley Online Library
Estimates of the risk of dementia in Parkinson's disease (PDD) vary widely. We aimed to
review the incidence of PDD and in a meta‐analysis estimate the pooled annual incidence …

The New Zealand Parkinson's progression programme

MR MacAskill, TL Pitcher, TR Melzer… - Journal of the Royal …, 2023 - Taylor & Francis
ABSTRACT We describe the New Zealand Parkinson's Progression Programme (NZP3), its
goals, findings, and future plans. To date, 354 people with Parkinson's disease and 89 …

Neuropsychiatric Symptoms and Parkinson Disease

RM Camicioli, C Colosimo - Neurology, 2023 - AAN Enterprises
Neuropsychiatric symptoms (NPS) include apathy, emotional dysregulation, impulse control
disorders, social inappropriateness, and abnormal perception or thought content. 1 Such …

Contribution of amyloid and putative Lewy body pathologies in neuropsychiatric symptoms

T Matsuoka, J Narumoto, F Morii‐Kitani… - … Journal of Geriatric …, 2023 - Wiley Online Library
Objectives Neuropsychiatric symptom could be useful for detecting patients with prodromal
dementia. Similarities and differences in the NPSs between preclinical/prodromal …