Parkinson's disease is a neurodegenerative disease whose progression and clinical
characteristics have a close bidirectional and multilevel relationship with the process of …

Synucleinopathies are neurodegenerative disorders characterized by alpha-synuclein
(αSyn) accumulation in neurons or glial cells, including Parkinson's disease (PD), dementia …

Besides motor symptoms, many individuals with Parkinson's disease develop cognitive
impairment perhaps due to coexisting α-synuclein and Alzheimer's disease pathologies and …

Background Persons with Parkinson's disease (PD) differentially progress to cognitive
impairment and dementia. With a 3-year longitudinal sample of initially non-demented PD …

Objective Anxiety, depression, and apathy are the most common neuropsychiatric symptoms
in Parkinson's disease (PD) patients. They impair cognitive functioning and have a profound …

Objectives The aim of this review is to provide an overview on prevalence and clinical tools
for the diagnosis of apathy, as well as on neurophysiological and neuroimaging findings …

Estimates of the risk of dementia in Parkinson's disease (PDD) vary widely. We aimed to
review the incidence of PDD and in a meta‐analysis estimate the pooled annual incidence …

ABSTRACT We describe the New Zealand Parkinson's Progression Programme (NZP3), its
goals, findings, and future plans. To date, 354 people with Parkinson's disease and 89 …

Neuropsychiatric symptoms (NPS) include apathy, emotional dysregulation, impulse control
disorders, social inappropriateness, and abnormal perception or thought content. 1 Such …

Objectives Neuropsychiatric symptom could be useful for detecting patients with prodromal
dementia. Similarities and differences in the NPSs between preclinical/prodromal …