Neurogenic background for emotional stress-associated hypertension

MAP Fontes, FR Marins, TA Patel, CA de Paula… - Current hypertension …, 2023 - Springer
Abstract Purpose of Review The response to natural stressors involves both cardiac
stimulation and vascular changes, primarily triggered by increases in sympathetic activity …

The central nervous mechanism of stress-promoting cancer progression

Y Hong, L Zhang, N Liu, X Xu, D Liu, J Tu - International journal of …, 2022 - mdpi.com
Evidence shows that stress can promote the occurrence and development of tumors. In
recent years, many studies have shown that stress-related hormones or peripheral …

The pupillary light reflex as a biomarker of concussion

FR Carrick, SF Azzolino, M Hunfalvay, G Pagnacco… - Life, 2021 - mdpi.com
The size of our pupils changes continuously in response to variations in ambient light levels,
a process known as the pupillary light reflex (PLR). The PLR is not a simple reflex as its …

An angiotensin-responsive connection from the lamina terminalis to the paraventricular nucleus of the hypothalamus evokes vasopressin secretion to increase blood …

CJ Frazier, SW Harden, AR Alleyne… - Journal of …, 2021 - Soc Neuroscience
Blood pressure is controlled by endocrine, autonomic, and behavioral responses that
maintain blood volume and perfusion pressure at levels optimal for survival. Although it is …

Interleukin 6 (IL-6) Regulates GABAA Receptors in the Dorsomedial Hypothalamus Nucleus (DMH) through Activation of the JAK/STAT pathway to affect heart rate …

L Zhang, W Shi, J Liu, K Chen, G Zhang… - International Journal of …, 2023 - mdpi.com
The dorsomedial hypothalamus nucleus (DMH) is an important component of the autonomic
nervous system and plays a critical role in regulating the sympathetic outputs of the heart …

High-Performance Bidirectional Microelectrode Array for Assessing Sevoflurane Anesthesia Effects and In Situ Electrical Stimulation in Deep Brain Regions

Q Jia, Y Duan, Y Liu, J Liu, J Luo, Y Song, Z Xu… - ACS …, 2024 - ACS Publications
Precise assessment of wakefulness states during sevoflurane anesthesia and timely arousal
are of paramount importance to refine the control of anesthesia. To tackle this issue, a …

Central stress pathways in the development of cardiovascular disease

J Braun, M Patel, T Kameneva, C Keatch… - Clinical Autonomic …, 2024 - Springer
Purpose Mental stress is of essential consideration when assessing cardiovascular
pathophysiology in all patient populations. Substantial evidence indicates associations …

Tachycardia evoked from insular stroke in rats is dependent on glutamatergic neurotransmission in the dorsomedial hypothalamus

FR Marins, M Limborço‐Filho… - European Journal of …, 2021 - Wiley Online Library
Background and purpose Damage to the insula results in cardiovascular complications. In
rats, activation of N‐methyl‐d‐aspartate receptors (NMDARs) in the intermediate region of …

Electrophysiological complexity in the rat dorsomedial hypothalamus and its susceptibility to daily rhythms and high‐fat diet

AM Sanetra, K Palus‐Chramiec… - European Journal of …, 2022 - Wiley Online Library
The dorsomedial hypothalamus (DMH) in amongst the most important brain structures
involved in the regulation of feeding behaviour and metabolism. In contrast to other …

Orexin-A directly depolarizes dorsomedial hypothalamic neurons, including those innervating the rostral ventrolateral medulla

TL Li, YH Lee, FH Wu, LL Hwang - European Journal of Pharmacology, 2021 - Elsevier
The dorsomedial hypothalamus (DMH) receives dense orexinergic innervation. Intra-DMH
application of orexins increases arterial pressure and heart rate in rats. We studied the …