Flavonoids: Overview of biosynthesis, biological activity, and current extraction techniques

S Liga, C Paul, F Péter - Plants, 2023 - mdpi.com
Recently, increased attention has been paid to natural sources as raw materials for the
development of new added-value products. Flavonoids are a large family of polyphenols …

Flavonoids on diabetic nephropathy: advances and therapeutic opportunities

Q Hu, C Qu, X Xiao, W Zhang, Y Jiang, Z Wu, D Song… - Chinese medicine, 2021 - Springer
With the advances in biomedical technologies, natural products have attracted substantial
public attention in the area of drug discovery. Flavonoids are a class of active natural …

Flavonoid production: current trends in plant metabolic engineering and de novo microbial production

H Tariq, S Asif, A Andleeb, C Hano, BH Abbasi - Metabolites, 2023 - mdpi.com
Flavonoids are secondary metabolites that represent a heterogeneous family of plant
polyphenolic compounds. Recent research has determined that the health benefits of fruits …

Bacterial biosynthesis of flavonoids: Overview, current biotechnology applications, challenges, and prospects

CO Okoye, H Jiang, Y Wu, X Li, L Gao… - Journal of Cellular …, 2023 - Wiley Online Library
Flavonoids are secondary metabolites present in plant organs and tissues. These natural
metabolites are the most prevalent and display a wide range of beneficial physiological …

Protective potential of hydroxysafflor yellow A in cerebral ischemia and reperfusion injury: An overview of evidence from experimental studies

L Yu, Z Jin, M Li, H Liu, J Tao, C Xu, L Wang… - Frontiers in …, 2022 - frontiersin.org
Ischemic stroke, mostly caused by thromboembolic or thrombotic arterial occlusions, is a
primary leading cause of death worldwide with high morbidity and disability. Unfortunately …

[HTML][HTML] 3′-8 ″-Biflavones: A Review of Their Structural Diversity, Natural Occurrence, Role in Plants, Extraction and Identification

D Šamec, I Jurčević Šangut, E Karalija, B Šarkanj… - Molecules, 2024 - mdpi.com
Dimeric forms of flavonoids, known as biflavonoids, are much less studied compared to
monomeric forms. It is estimated that nearly 600 different natural biflavonoids have been …

Targeting lncRNA/Wnt axis by flavonoids: A promising therapeutic approach for colorectal cancer

S Han, Y Cao, T Guo, Q Lin, F Luo - Phytotherapy Research, 2022 - Wiley Online Library
Despite the dramatic advances in our understanding of the etiology of colorectal cancer
(CRC) in recent decades, effective therapeutic strategies are still urgently needed …

Potential psychoactive effects of microalgal bioactive compounds for the case of sleep and mood regulation: Opportunities and challenges

B McCarthy, G O'Neill, N Abu-Ghannam - Marine Drugs, 2022 - mdpi.com
Sleep deficiency is now considered an emerging global epidemic associated with many
serious health problems, and a major cause of financial and social burdens. Sleep and …

Integrated metabolome and transcriptome analysis reveals the regulatory mechanism of low nitrogen-driven biosynthesis of saponins and flavonoids in Panax …

Z Cun, JY Zhang, J Hong, J Yang, LL Gao, B Hao… - Gene, 2024 - Elsevier
Background Nitrogen (N) is an important macronutrient involved in the biosynthesis of
primary and secondary metabolites in plants. However, the metabolic regulatory mechanism …

Phenolic C-glycoside synthesis using microbial systems

Y Chong, SW Lee, JH Ahn - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•Plants synthesize a variety of phenolic C-glycosides having diverse biological
activity.•The genes in charge of phenolic compounds C-glycosyltransferases (CGTs) have …