Macrophages are versatile and heterogeneous innate immune cells undertaking central
functions in balancing immune responses and tissue repair to maintain homeostasis. This …

In religious philosophy, the concept of karma represents the effect of one's past and present
actions on one's future. Macrophages are highly plastic cells with myriad roles in health and …

The genetic circuits that allow cancer cells to evade immune killing via epithelial
mesenchymal plasticity remain poorly understood. Here, we showed that mesenchymal-like …

Abstract Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the
tumour microenvironment. Their roles in the cancer immunity are complicated, both pro …

Background Colorectal cancer (CRC) is the second most common cause of cancer-related
deaths worldwide. Tumor metastasis and CD8+ T cell infiltration play a crucial role in CRC …

Successful antitumor immunity largely relies on efficient T cell priming by antigen-presenting
cells (APCs); however, the capacity of APCs is found to be defective in many cancers …

Malignant mesothelioma (MESO) consists of epithelioid, biphasic, and sarcomatoid
subtypes with different epithelial–mesenchymal transition (EMT) phenotypes. We previously …

Abstract Purpose of Review The purpose of this review is to summarize the recently
published findings regarding the role of epithelial to mesenchymal transition (EMT) in tumor …

Curcuminoids, which include natural acyclic diarylheptanoids and the synthetic analogs of
curcumin, have considerable potential for fighting against all the characteristics of invasive …

Disease recurrence and drug resistance are major challenges in the clinical management of
patients with colorectal cancer liver metastases (CLM), and because tumors are generally …