Mechanistic connections between endoplasmic reticulum (ER) redox control and mitochondrial metabolism

Y Fan, T Simmen - Cells, 2019 - mdpi.com
The past decade has seen the emergence of endoplasmic reticulum (ER) chaperones as
key determinants of contact formation between mitochondria and the ER on the …

Cell-autonomous metabolic reprogramming in hypoxia

L Schito, S Rey - Trends in cell biology, 2018 - cell.com
Molecular oxygen (O 2) is a universal electron acceptor that enables ATP synthesis through
mitochondrial respiration in all metazoans. Consequently, hypoxia (low O 2) has arisen as …

Anoxic induction of ATF-4 through HIF-1–independent pathways of protein stabilization in human cancer cells

K Ameri, CE Lewis, M Raida, H Sowter, T Hai… - Blood, 2004 - ashpublications.org
Hypoxia is a key factor in tumor development, contributing to angiogenesis and radiotherapy
resistance. Hypoxia-inducible factor-1 (HIF-1) is a major transcription factor regulating the …

EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor

DC Sullivan, L Huminiecki, JW Moore, JJ Boyle… - Journal of Biological …, 2003 - ASBMB
We have identified a novel protein-disulfide isomerase and named it endothelial protein-
disulfide isomerase (EndoPDI) because of its high expression in endothelial cells. Isolation …

Rapid induction of a protein disulfide isomerase and defense-related genes in wheat in response to the hemibiotrophic fungal pathogen Mycosphaerella graminicola

S Ray, JM Anderson, FI Urmeev, SB Goodwin - Plant molecular biology, 2003 - Springer
Mycosphaerella graminicola, incitant of septoria tritici blotch, is a widespread and significant
pathogen of wheat that is not closely related to other fungi being developed as genetic …

Роль сосудистого эндотелия в организме и универсальные механизмы изменения его активности (обзор литературы)

НН Дорофиенко - Бюллетень физиологии и патологии дыхания, 2018 - cyberleninka.ru
В обзоре литературы обобщены и изложены результаты исследований биологической
роли сосудистого эндотелия в организме, универсальные механизмы регуляции его …

Hypoxia and reactive oxygen species as modulators of endoplasmic reticulum and Golgi homeostasis

D Mennerich, S Kellokumpu… - Antioxidants & redox …, 2019 - liebertpub.com
Significance: Eukaryotic cells execute various functions in subcellular compartments or
organelles for which cellular redox homeostasis is of importance. Apart from mitochondria …

[HTML][HTML] Inhibition of protein disulfide isomerase in glioblastoma causes marked downregulation of DNA repair and DNA damage response genes

S Xu, Y Liu, K Yang, H Wang, A Shergalis, A Kyani… - Theranostics, 2019 - ncbi.nlm.nih.gov
Aberrant overexpression of endoplasmic reticulum (ER)-resident oxidoreductase protein
disulfide isomerase (PDI) plays an important role in cancer progression. In this study, we …

Novel role of protein disulfide isomerase in the regulation of NADPH oxidase activity: pathophysiological implications in vascular diseases

FRM Laurindo, DC Fernandes, AM Amanso… - Antioxidants & redox …, 2008 - liebertpub.com
Vascular cell NADPH oxidase complexes are key sources of signaling reactive oxygen
species (ROS) and contribute to disease pathophysiology. However, mechanisms that fine …

In-vitro and in-vivo evaluation of the molecular mechanisms involved in the toxicity associated to CdSe/ZnS quantum dots exposure

E Garcia-Calvo, P Cabezas-Sanchez, JL Luque-Garcia - Chemosphere, 2021 - Elsevier
The use of different types of quantum dots is growing in recent times in both the technology
and biomedical industries. Such is the extension of the use of these quantum dots that they …