Bone vasculature plays a vital role in bone development, remodeling and homeostasis. New
blood vessel formation is crucial during both primary bone development as well as fracture …

The repair of large bone defects remains a major clinical orthopaedic challenge. Bone is a
highly vascularised tissue reliant on the close spatial and temporal connection between …

There have been extensive research efforts to develop new strategies for bone tissue
engineering. These have mainly focused on vascularization during the development and …

The pharmacokinetic properties of a drug can be significantly improved by the delivery
process. Scientists have understood that developing suitable drug delivery systems that …

Stem cell therapy offers potential in the regeneration of craniofacial bone defects; however, it
has not been studied clinically. Tissue repair cells (TRCs) isolated from bone marrow …

Cellular strategies play an important role in bone tissue engineering and regenerative
medicine (BTE/RM). Variability in cell culture procedures (eg, cell types, cell isolation and …

The ability to create thick tissues is a major tissue engineering challenge, requiring the
development of a suitable vascular supply. Current trends are seeing the utilization of cells …

OBJECTIVES: The clinical translation of stem cell-based Regenerative Endodontics
demands further development of suitable injectable scaffolds. Puramatrix™ is a defined, self …

Stem cells from human exfoliated deciduous teeth have been identified as a new post-natal
stem cell population with multipotential differentiation capabilities, including regeneration of …

The tremendous need for bone tissue in numerous clinical situations and the limited
availability of suitable bone grafts are driving the development of tissue engineering …