Highs and lows of hyperoxia: physiological, performance, and clinical aspects

JV Brugniaux, GB Coombs, OF Barak… - American Journal …, 2018 - journals.physiology.org
Molecular oxygen (O2) is a vital element in human survival and plays a major role in a
diverse range of biological and physiological processes. Although normobaric hyperoxia …

The effects of hyperoxia on sea-level exercise performance, training, and recovery: a meta-analysis

MM Mallette, DG Stewart, SS Cheung - Sports Medicine, 2018 - Springer
Background Acute exercise performance can be limited by arterial hypoxemia, such that
hyperoxia may be an ergogenic aid by increasing tissue oxygen availability. Hyperoxia …

Effect of breathing oxygen-enriched air on exercise performance in patients with precapillary pulmonary hypertension: randomized, sham-controlled cross-over trial

S Ulrich, ED Hasler, S Saxer, M Furian… - European Heart …, 2017 - academic.oup.com
Aims The purpose of the current trial was to test the hypothesis that breathing oxygen-
enriched air increases exercise performance of patients with pulmonary arterial or chronic …

Effect of domiciliary oxygen therapy on exercise capacity and quality of life in patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension: a …

S Ulrich, S Saxer, ED Hasler, EI Schwarz… - European …, 2019 - Eur Respiratory Soc
Study question We investigated whether domiciliary oxygen therapy (DOXT) increases
exercise capacity and quality of life in patients with pulmonary arterial or distal chronic …

Effect of hypoxia and hyperoxia on exercise performance in healthy individuals and in patients with pulmonary hypertension: a systematic review

S Ulrich, SR Schneider… - Journal of Applied …, 2017 - journals.physiology.org
Exercise performance is determined by oxygen supply to working muscles and vital organs.
In healthy individuals, exercise performance is limited in the hypoxic environment at altitude …

Acute hemodynamic changes by breathing hypoxic and hyperoxic gas mixtures in pulmonary arterial and chronic thromboembolic pulmonary hypertension

A Groth, S Saxer, PR Bader, M Lichtblau… - International journal of …, 2018 - Elsevier
Background There is insufficient evidence to counsel patients with pulmonary hypertension
undergoing altitude or air travel. We thus aimed to study hemodynamic response of patients …

Effect of normobaric hypoxia on exercise performance in pulmonary hypertension: randomized trial

SR Schneider, LC Mayer, M Lichtblau, C Berlier… - Chest, 2021 - Elsevier
Background Many patients with pulmonary arterial or chronic thromboembolic pulmonary
hypertension (PH) wish to travel to altitude or by airplane, but their risk of hypoxia-related …

Effect of a day-trip to altitude (2500 m) on exercise performance in pulmonary hypertension: randomised crossover trial

SR Schneider, LC Mayer, M Lichtblau… - ERJ Open …, 2021 - Eur Respiratory Soc
Question addressed by the study To investigate exercise performance and hypoxia-related
health effects in patients with pulmonary hypertension (PH) during a high-altitude sojourn …

Exertional desaturation in idiopathic pulmonary fibrosis: the role of oxygen supplementation in modifying cerebral-skeletal muscle oxygenation and systemic …

K Dipla, AK Boutou, A Markopoulou, G Pitsiou… - Respiration, 2021 - karger.com
Background: In patients with idiopathic pulmonary fibrosis (IPF) with isolated exertional
desaturation, there are limited data regarding the effectiveness of oxygen supplementation …

Clinician's corner: counseling patients with pulmonary vascular disease traveling to high altitude

S Ulrich, M Lichtblau, SR Schneider… - … Altitude Medicine & …, 2022 - liebertpub.com
Ulrich, Silvia, Mona Lichtblau, Simon R. Schneider, Stéphanie Saxer, and Konrad E. Bloch,
Clinician's corner: counseling patients with pulmonary vascular disease traveling to high …