Mechanism of drug-induced liver injury and hepatoprotective effects of natural drugs
Y Zhou, J Wang, D Zhang, J Liu, Q Wu, J Chen, P Tan… - Chinese medicine, 2021 - Springer
Drug-induced liver injury (DILI) is a common adverse drug reaction (ADR) and a serious
threat to health that affects disease treatments. At present, no targeted clinical drugs are …
threat to health that affects disease treatments. At present, no targeted clinical drugs are …
[HTML][HTML] Push forward LC-MS-based therapeutic drug monitoring and pharmacometabolomics for anti-tuberculosis precision dosing and comprehensive clinical …
The spread of tuberculosis (TB), especially multidrug-resistant TB and extensively drug-
resistant TB, has strongly motivated the research and development of new anti-TB drugs …
resistant TB, has strongly motivated the research and development of new anti-TB drugs …
Prebiotic-like cyclodextrin assisted silybin on NAFLD through restoring liver and gut homeostasis
L Ren, XL Ma, HL Wang, R Li, JJ Cui, PJ Yan… - Journal of Controlled …, 2022 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease with no
currently approved treatment. The natural compound silybin (SLN) has versatile …
currently approved treatment. The natural compound silybin (SLN) has versatile …
Carvacrol promotes angiogenic paracrine potential and endothelial differentiation of human mesenchymal stem cells at low concentrations
D Matluobi, A Araghi, BFA Maragheh… - Microvascular …, 2018 - Elsevier
Objectives Phenolic monoterpene compound, named Carvacrol, has been found to exert
different biological outcomes. It has been accepted that the angiogenic activity of human …
different biological outcomes. It has been accepted that the angiogenic activity of human …
Hepatoprotective Effect of Steroidal Glycosides From Dioscorea villosa on Hydrogen Peroxide-Induced Hepatotoxicity in HepG2 Cells
Dioscorea villosa, commonly known as “Wild Yam” and native to North America, is well
documented for its pharmacological properties due to the presence of steroidal glycosides …
documented for its pharmacological properties due to the presence of steroidal glycosides …
Rifampicin-induced injury in HepG2 cells is alleviated by TUDCA via increasing bile acid transporters expression and enhancing the Nrf2-mediated adaptive response
W Zhang, L Chen, H Feng, W Wang, Y Cai, F Qi… - Free Radical Biology …, 2017 - Elsevier
Bile acid transporters and the nuclear factor erythroid 2-related factor (Nrf-2)-mediated
adaptive response play important roles in the development of drug-induced liver injury …
adaptive response play important roles in the development of drug-induced liver injury …
[HTML][HTML] Additional compounds and the therapeutic potential of Cnidoscolus chayamansa (McVaugh) against hepatotoxicity induced by antitubercular drugs
MZ Pérez-González, ML Macías-Rubalcava… - Biomedicine & …, 2019 - Elsevier
Previously non-isolated compounds (scopoletin and β-D-Glucopyranoside,(1R)-O-isopropyl
6-O-(2, 3, 4-tri-O-acetyl-β-D-xylopyranosyl)-2, 3, 4-triacetate) were isolated from an organic …
6-O-(2, 3, 4-tri-O-acetyl-β-D-xylopyranosyl)-2, 3, 4-triacetate) were isolated from an organic …
Rhizophora mucronata Lam. (Mangrove) Bark Extract Reduces Ethanol-Induced Liver Cell Death and Oxidative Stress in Swiss Albino Mice: In Vivo and In Silico …
C Jairaman, ZI Alehaideb, SAM Yacoob, SS Alghamdi… - Metabolites, 2022 - mdpi.com
The bark extract of Rhizophora mucronata (BERM) was recently reported for its prominent in
vitro protective effects against liver cell line toxicity caused by various toxicants, including …
vitro protective effects against liver cell line toxicity caused by various toxicants, including …
Pentacyclic triterpenoid saponins, poterinasides A–J, from Silverweed Cinquefoil Roots promising hepatoprotective and anti-inflammatory Agents
D Yang, N Han, YW Wang, JX Zhai, ZH Liu… - The Journal of …, 2021 - ACS Publications
Silverweed cinquefoil roots, as dietary supplements, foods, and medicines, are widely used
in western areas of China, specifically in Tibet Autonomous Region and Gansu and Qinghai …
in western areas of China, specifically in Tibet Autonomous Region and Gansu and Qinghai …
Protective Effect of Annona muricata Linn Fruit Pulp Lyophilized Powder against Paracetamol-Induced Redox Imbalance and Hepatotoxicity in Rats
S Menon, RA Al-Eisa, H Hamdi, L Lawrence… - Processes, 2023 - mdpi.com
In the current investigation, Annona muricata Linn. lyophilized fruit pulp powder was
evaluated for its hepatoprotective activity induced by paracetamol or acetaminophen …
evaluated for its hepatoprotective activity induced by paracetamol or acetaminophen …