[HTML][HTML] Metastatic disease in head & neck oncology

P Pisani, M Airoldi, A Allais, PA Valletti… - Acta …, 2020 - ncbi.nlm.nih.gov
The head and neck district represents one of the most frequent sites of cancer, and the
percentage of metastases is very high in both loco-regional and distant areas. Prognosis …

Expert consensus document on pulmonary metastasectomy

JR Handy, RM Bremner… - The Annals of …, 2019 - annalsthoracicsurgery.org
17. When managing NSGCTs, PM is indicated for select patients with limited number of lung
abnormalities after first-line or second-line platin-based chemotherapy suspected of …

circRNA_0000140 suppresses oral squamous cell carcinoma growth and metastasis by targeting miR-31 to inhibit Hippo signaling pathway

QS Peng, YN Cheng, WB Zhang, H Fan, QH Mao… - Cell Death & …, 2020 - nature.com
Oral squamous cell carcinoma (OSCC) is one of the most common malignancies and has a
poor prognosis. Circular RNA (circRNA) has been increasingly recognized as a crucial …

[HTML][HTML] EPHB2 carried on small extracellular vesicles induces tumor angiogenesis via activation of ephrin reverse signaling

S Sato, S Vasaikar, A Eskaros, Y Kim, JS Lewis… - JCI insight, 2019 - ncbi.nlm.nih.gov
Angiogenesis is a key process that allows nutrient uptake and cellular trafficking and is
coopted in cancer to enable tumor growth and metastasis. Recently, extracellular vesicles …

Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases

P Jurmeister, M Bockmayr, P Seegerer… - Science Translational …, 2019 - science.org
Head and neck squamous cell carcinoma (HNSC) patients are at risk of suffering from both
pulmonary metastases or a second squamous cell carcinoma of the lung (LUSC) …

TMEM16A as a potential treatment target for head and neck cancer

K Okuyama, S Yanamoto - Journal of Experimental & Clinical Cancer …, 2022 - Springer
Abstract Transmembrane protein 16A (TMEM16A) forms a plasma membrane-localized
Ca2+-activated Cl-channel. Its gene has been mapped to an area on chromosome 11q13 …

Management of recurrent and metastatic oral cavity cancer: Raising the bar a step higher

P Szturz, JB Vermorken - Oral oncology, 2020 - Elsevier
In recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M-
SCCHN), the armamentarium of systemic anti-cancer modalities continues to grow in …

Circulating tumour cells in metastatic head and neck cancers

A Kulasinghe, C Perry, L Jovanovic… - … journal of cancer, 2015 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with
650,000 new cases p/a worldwide. HNSCC causes high morbidity with a 5‐year survival …

Current therapeutic strategies for patients with hypopharyngeal carcinoma: oncologic and functional outcomes

A Bozec, G Poissonnet, O Dassonville… - Journal of Clinical …, 2023 - mdpi.com
Hypopharyngeal cancer is usually diagnosed at an advanced stage and is associated with a
high risk of recurrence and poor survival rates. Although they differ greatly in terms of …

Patterns of distant metastasis in head and neck cancer at presentation: implications for initial evaluation

JC Liu, M Bhayani, K Kuchta, T Galloway… - Oral oncology, 2019 - Elsevier
Importance Evaluation of distant metastasis (DM) is part of every new cancer evaluation.
Understanding DM presentation patterns may impact the imaging workup of Head and Neck …