Inflammation, immune activation, and antiretroviral therapy in HIV

CO Hileman, NT Funderburg - Current Hiv/aids reports, 2017 - Springer
Abstract Purpose of Review This review focuses on the differential effects of contemporary
antiretrovirals on systemic inflammation as heightened immune activation is linked to …

Metabolic complications affecting adipose tissue, lipid and glucose metabolism associated with HIV antiretroviral treatment

C Lagathu, V Béréziat, J Gorwood… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Efficient antiretroviral-treatment (ART) generally allows control of HIV infection.
However, persons-living-with-HIV (PLWH), when aging, present a high prevalence of …

Greater weight gain in treatment-naive persons starting dolutegravir-based antiretroviral therapy

K Bourgi, PF Rebeiro, M Turner… - Clinical Infectious …, 2020 - academic.oup.com
Background Recent studies have reported weight gain in virologically suppressed persons
living with human immunodeficiency virus (PLWH) switched from older antiretroviral therapy …

Antiretroviral treatment of adult HIV infection: 2014 recommendations of the International Antiviral Society–USA Panel

HF Günthard, JA Aberg, JJ Eron, JF Hoy, A Telenti… - Jama, 2014 - jamanetwork.com
Importance New data and antiretroviral regimens expand treatment choices in resource-rich
settings and warrant an update of recommendations to treat adults infected with human …

Residual immune dysregulation syndrome in treated HIV infection

MM Lederman, NT Funderburg, RP Sekaly… - Advances in …, 2013 - Elsevier
Antiretroviral therapy has revolutionized the course of HIV infection, improving immune
function and decreasing dramatically the mortality and morbidity due to the opportunistic …

Management of inflammation in cardiovascular diseases

SK Goswami, P Ranjan, RK Dutta, SK Verma - Pharmacological research, 2021 - Elsevier
Cardiovascular disease is the leading cause of morbidity and mortality world-wide. Recently,
the role of inflammation in the progression of diseases has significantly attracted …

Cardiovascular risk and dyslipidemia among persons living with HIV: a review

P Maggi, A Di Biagio, S Rusconi, S Cicalini… - BMC infectious …, 2017 - Springer
Background Aim of this review is to focus the attention on people living with HIV infection at
risk of developing a cardiovascular event. What is or what would be the most suitable …

HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration

A Cooper, M García, C Petrovas, T Yamamoto… - Nature, 2013 - nature.com
Abstract Human immunodeficiency virus-1 (HIV-1) has infected more than 60 million people
and caused nearly 30 million deaths worldwide, ultimately the consequence of cytolytic …

Factors associated with plasma IL-6 levels during HIV infection

ÁH Borges, JL O'Connor, AN Phillips… - The Journal of …, 2015 - academic.oup.com
Abstract Background. Elevated interleukin 6 (IL-6) levels have been linked to cardiovascular
disease, cancer and death. Persons with human immunodeficiency virus (HIV) infection …

Metabolic disease in HIV infection

JE Lake, JS Currier - The Lancet infectious diseases, 2013 - thelancet.com
The treatment of metabolic disease is becoming an increasingly important component of the
long-term management of patients with well controlled HIV on antiretroviral therapy (ART) …