NAFLD as a sexual dimorphic disease: role of gender and reproductive status in the development and progression of nonalcoholic fatty liver disease and inherent …

S Ballestri, F Nascimbeni, E Baldelli, A Marrazzo… - Advances in …, 2017 - Springer
Nonalcoholic fatty liver disease (NAFLD) spans steatosis through nonalcoholic
steatohepatis, cirrhosis, and hepatocellular carcinoma (HCC) associated with striking …

The influence of sex hormones in liver function and disease

A Kasarinaite, M Sinton, PTK Saunders, DC Hay - Cells, 2023 - mdpi.com
The liver performs a multitude of bodily functions, whilst retaining the ability to regenerate
damaged tissue. In this review, we discuss sex steroid biology, regulation of mammalian …

[HTML][HTML] Nonalcoholic fatty liver disease and aging: epidemiology to management

M Bertolotti, A Lonardo, C Mussi, E Baldelli… - World journal of …, 2014 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is common in the elderly, in whom it carries a more
substantial burden of hepatic (nonalcoholic steatohepatitis, cirrhosis and hepatocellular …

The epidemiology of nonalcoholic fatty liver disease: a global perspective

M Lazo, JM Clark - Seminars in liver disease, 2008 - thieme-connect.com
Nonalcoholic fatty liver disease (NAFLD) is an increasingly recognized cause of liver
disease in the United States and worldwide. With obesity being an important risk factor …

Sex hormones and their receptors regulate liver energy homeostasis

M Shen, H Shi - International journal of endocrinology, 2015 - Wiley Online Library
The liver is one of the most essential organs involved in the regulation of energy
homeostasis. Hepatic steatosis, a major manifestation of metabolic syndrome, is associated …

Gender medicine: a task for the third millennium

G Baggio, A Corsini, A Floreani, S Giannini… - Clinical Chemistry and …, 2013 - degruyter.com
Gender-specific medicine is the study of how diseases differ between men and women in
terms of prevention, clinical signs, therapeutic approach, prognosis, psychological and …

A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet

G Yang, HE Lee, JY Lee - Scientific reports, 2016 - nature.com
The activation of NOD-like receptor family pyrin domain containing 3 (NLRP3)
inflammasome is closely associated with the development and progression of non-alcoholic …

Non-alcoholic fatty liver disease and cardiovascular risk

A Brea, J Puzo - International journal of cardiology, 2013 - Elsevier
The term “Non-alcoholic fatty liver disease”(NAFLD) covers a series of liver lesions similar to
those induced by alcohol, but not caused by alcohol use. The importance of NAFLD lies in …

Nonalcoholic fatty liver disease in women

A Suzuki, MF Abdelmalek - Women's health, 2009 - journals.sagepub.com
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in
developed countries and is increasing in prevalence with the rise of diabetes and obesity. In …

LiverSex Computational Model: Sexual Aspects in Hepatic Metabolism and Abnormalities

T Cvitanović Tomaš, Ž Urlep, M Moškon… - Frontiers in …, 2018 - frontiersin.org
The liver is to date the best example of a sexually dimorphic non-reproductive organ. Over
1,000 genes are differentially expressed between sexes indicating that female and male …