Tumour metastasis is the main cause of cancer related deaths. Metastasis is an intricate
multi-step process that requires the acquisition of several cancer cell features, including the …

Despite advances in understanding the development and progression of cancer in recent
years, there remains a lack of comprehensive characterization of the cancer glycoproteome …

Integrins are transmembrane receptors that coordinate extracellular matrix (ECM)–cell and
cell–cell interactions, signal transmission, gene expression, and cell function. The aberration …

Extracellular matrix (ECM) macromolecules together with a multitude of different molecules
residing in the extracellular space play a vital role in the regulation of cellular phenotype and …

Background: Small cell lung cancer (SCLC) is an extremely aggressive cancer type with a
patient median survival of 6-12 months. Epidermal growth factor (EGF) signaling plays an …

Transmembrane-4 L-six family member-1 (TM4SF1) is a member of the L6 family and
functions as a signal transducer to regulate tumor cell behaviors. However, the function and …

Simple Summary Pancreatic cancer (PC) is a highly aggressive malignant tumor with an
extremely poor prognosis. Early diagnosis and treatment are key to improving the survival …

Abstract The α2, 3‐sialylation of N‐glycans is considered important but complicated
because the functions of the three β‐galactoside α2, 3‐sialyltransferases, ST3GAL3 …

Integrins contribute to cancer progression and aggressiveness by activating intracellular
signal transduction pathways and transducing mechanical tension forces. Remarkably …

Aberrant protein phosphorylation and glycosylation are closely associated with a number of
diseases. In particular, an interplay between phosphorylation and glycosylation regulates …