Antimalarial chemotherapy is one of the main pillars in the prevention and control of malaria.
Following widespread resistance of Plasmodium falciparum to chloroquine, sulfadoxine …

CRISPR guide RNA sequences deriving exactly from natural sequences may not perform
optimally in every application. Here we implement and evaluate algorithms for designing …

Salmonella spp., a leading cause of foodborne illness, is a formidable global menace due to
escalating antimicrobial resistance (AMR). The evaluation of minimum inhibitory …

Plasmodium falciparum, the most virulent agent of human malaria, spread from Africa to all
continents following the out-of-Africa human migrations. During the transatlantic slave trade …

Abstract Haiti and the Dominican Republic, which share the island of Hispaniola, are the last
locations in the Caribbean where malaria still persists. Malaria is an important public health …

This important new book provides innovative material, including peer-reviewed chapters
and survey articles on new applied research and development, in the scientifically important …

Hispaniola, comprising Haiti and the Dominican Republic, has been identified as a
candidate for malaria elimination. However, incomplete surveillance data in Haiti hamper …

Abstract Background In Haiti where chloroquine (CQ) is widely used for malaria treatment,
reports of resistance are scarce. However, recent identification of CQ resistance genotypes …

Haiti is striving for zero local malaria transmission by the year 2025. Chloroquine remains
the first-line treatment, and sulfadoxine/pyrimethamine (SP) has been used for mass drug …

Chloroquine (CQ) remains the first-line treatment of malaria in Haiti. Given the challenges of
conducting in vivo drug efficacy trials in low-endemic settings like Haiti, molecular …