Large-conductance Ca2+-and voltage-activated K+ (BK) channels play many physiological
roles ranging from the maintenance of smooth muscle tone to hearing and neurosecretion …

Potassium channels are particularly important in determining the shape and duration of the
action potential, controlling the membrane potential, modulating hormone secretion …

Different calcium signals in the endothelium and smooth muscle target different types of
Ca2+-sensitive K+ channels to modulate vascular function. These differential calcium …

Ion channels in vascular smooth muscle regulate myogenic tone and vessel contractility. In
particular, activation of calcium-and voltage-gated potassium channels of large conductance …

Ca2+-and voltage-gated K+ channels of large conductance (BK channels) are expressed in
a diverse variety of both excitable and inexcitable cells, with functional properties …

The basic functional unit of the large‐conductance, voltage‐and Ca2+‐activated K+ (MaxiK,
BK, BKCa) channel is a tetramer of the pore‐forming α‐subunit (MaxiKα) encoded by a …

Proteins with dibasic retention motifs are subject to retrograde transport to endoplasmic
reticulum (ER) by COPI-coated vesicles. As forward transport requires escape from ER …

We address advances in the understanding of myometrial physiology, focusing on excitation
and the effects of gestation on ion channels and their relevance to labor. This review moves …

The large conductance calcium‐and voltage‐activated potassium channel (BKCa) is widely
expressed at the plasma membrane. This channel is involved in a variety of fundamental …

Ion channels are effector proteins that mediate uterine excitability throughout gestation. This
review will focus primarily on the role of potassium channels in regulating myometrial tone in …