The psychosis spectrum in Parkinson disease

DH Ffytche, B Creese, M Politis, KR Chaudhuri… - Nature Reviews …, 2017 - nature.com
In 2007, the clinical and research profile of illusions, hallucinations, delusions and related
symptoms in Parkinson disease (PD) was raised with the publication of a consensus …

Parkinson's disease dementia: a neural networks perspective

J Gratwicke, M Jahanshahi, T Foltynie - Brain, 2015 - academic.oup.com
In the long-term, with progression of the illness, Parkinson's disease dementia affects up to
90% of patients with Parkinson's disease. With increasing life expectancy in western …

The clinical heterogeneity of Parkinson's disease and its therapeutic implications

JC Greenland, CH Williams‐Gray… - European Journal of …, 2019 - Wiley Online Library
Although Parkinson's disease (PD) is primarily a movement disorder, there are a range of
associated nonmotor symptoms, including cognitive impairment, depression and sleep …

The cholinergic brain in Parkinson's disease

J Pasquini, DJ Brooks, N Pavese - … Disorders Clinical Practice, 2021 - Wiley Online Library
The central cholinergic system includes the basal forebrain nuclei, mainly projecting to the
cortex, the mesopontine tegmental nuclei, mainly projecting to the thalamus and subcortical …

Minor hallucinations in Parkinson disease: a subtle symptom with major clinical implications

A Lenka, J Pagonabarraga, PK Pal, H Bejr-Kasem… - Neurology, 2019 - AAN Enterprises
Objective Psychosis is one of the most debilitating complications of Parkinson disease (PD).
Although research on PD psychosis has been focused on the study of well-structured visual …

Psychosis in Parkinson's disease: epidemiology, pathophysiology, and management

A Chang, SH Fox - Drugs, 2016 - Springer
Psychotic symptoms are common in Parkinson's disease (PD) and are associated with
poorer quality of life and increased caregiver burden. PD psychosis is correlated with …

Visuoperceptive region atrophy independent of cognitive status in patients with Parkinson's disease with hallucinations

JG Goldman, GT Stebbins, V Dinh, B Bernard… - Brain, 2014 - academic.oup.com
Visual hallucinations are frequent, disabling complications of advanced Parkinson's
disease, but their neuroanatomical basis is incompletely understood. Previous structural …

Atrophy of the cholinergic basal forebrain in dementia with Lewy bodies and Alzheimer's disease dementia

MJ Grothe, C Schuster, F Bauer, H Heinsen… - Journal of …, 2014 - Springer
Similar to Alzheimer's disease (AD), dementia with Lewy bodies (DLB) is characterized by a
profound degeneration of cortically-projecting cholinergic neurons of the basal forebrain …

Hallucinations, somatic‐functional disorders of PD‐DLB as expressions of thalamic dysfunction

M Onofrj, AJ Espay, L Bonanni, S Delli Pizzi… - Movement …, 2019 - Wiley Online Library
Hallucinations, delusions, and functional neurological manifestations (conversion and
somatic symptom disorders) of Parkinson's disease (PD) and dementia with Lewy bodies …

The metabolic pattern of idiopathic REM sleep behavior disorder reflects early-stage Parkinson disease

SK Meles, RJ Renken, A Janzen… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Idiopathic REM sleep behavior disorder (iRBD) is considered a prodromal stage of
Parkinson disease (PD) and other Lewy body disorders. Spatial covariance analysis of 18F …