Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Brain-derived neurotrophic factor (BDNF) is widely accepted for its involvement in resilience
and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and …

Exercise is a non-pharmacological strategy to mitigate the deleterious effects of aging on
brain health. However, a large amount of variation exists in its efficacy. Sex of participants …

With the aging of the population, the burden of Alzheimer's disease (AD) is rapidly
expanding. More than 5 million people in the US alone are affected with AD and this number …

Aging is an inevitable biological process characterized by a progressive decline in
physiological function and increased susceptibility to disease. The detrimental effects of …

Estrogens and estrogen-like molecules can modify the biology of several cell types.
Estrogen receptors alpha (ERα) and beta (ERβ) belong to the so-called classical family of …

Polyphenols are an important class of phytochemicals, and several lines of evidence have
demonstrated their beneficial effects in the context of a number of pathologies including …

During the past decade there has been a substantial advance in our understanding of
estrogen signaling both from a clinical as well as a preclinical perspective. Estrogen …

Brain‐derived neurotrophic factor (BDNF) is a neurotrophin, which plays an important role in
the central nervous system, and systemic or peripheral inflammatory conditions, such as …

This article is part of a Special Issue “Puberty and Adolescence”. Puberty is one of the most
frequently discussed risk periods for the development of eating disorders. Prevailing …