RNA molecules play fundamental roles in cellular processes. Their function and interactions
with other biomolecules are dependent on the ability to form complex three-dimensional …

Long non-coding RNAs (lncRNAs) are key regulatory molecules, but unlike with other RNAs,
the direct link between their tertiary structure motifs and their function has proven elusive …

Functional RNA molecules depend on three-dimensional (3D) structures to carry out their
tasks within the cell. Understanding how these molecules interact to carry out their biological …

RNA is now known to possess various structural, regulatory and enzymatic functions for
survival of cellular organisms. Functional RNA structures are generally created by three …

Direct coupling analysis of nucleotide coevolution provides a novel approach to identify
which nucleotides in an RNA molecule are likely in direct contact, and this information …

Group II introns are self-splicing, mobile genetic elements that have fundamentally
influenced the organization of terrestrial genomes. These large ribozymes remain important …

LOOS (Lightweight Object Oriented Structure‐analysis) is a C++ library designed to facilitate
making novel tools for analyzing molecular dynamics simulations by abstracting out the …

The bis-(3′-5′)-cyclic dimeric guanosine monophosphate (c-di-GMP) signaling pathway
regulates biofilm formation, virulence, and other processes in many bacterial species and is …

Single-stranded junctions/loops are frequently occurring structural motifs in nucleic acid
structures. Due to the polyanionic nature of the nucleic acid backbone, metal ions play a …

RNA pseudoknots play a critical role in RNA-related biology from the assembly of ribosome
to the regulation of viral gene expression. A predictive model for pseudoknot structure and …