[HTML][HTML] Recent advances in electrochemical sensors and biosensors for monitoring drugs and metabolites in pharmaceutical and biological samples

C Laghlimi, A Moutcine, A Chtaini, J Isaad, A Soufi… - ADMET and …, 2023 - hrcak.srce.hr
Sažetak Various applications of electrochemical sensors and biosensors have been
reported in many fields. These include pharmaceuticals, drug detection, cancer detection …

Disposable screen-printed electrodes modified with uniform iron oxide nanocubes for the simple electrochemical determination of meclizine, an antihistamine drug

AA Khorshed, M Khairy, SA Elsafty, CE Banks - Analytical Methods, 2019 - pubs.rsc.org
Meclizine (MEC) is an antihistamine drug with long action and moderate sedative effects. It
is commonly used in management of nausea, motion sickness and vomiting. Herein, a …

Voltammetric determination of meclizine antihistamine drug utilizing graphite screen-printed electrodes in physiological medium

AA Khorshed, M Khairy, CE Banks - Journal of Electroanalytical Chemistry, 2018 - Elsevier
Several classes of antihistamine drugs are widely distributed over the world's medication
although their intensive side effects are in the high dosages. In the present manuscript, we …

Chromatographic determination of sulfasalazine and its active metabolites: greenness assessment and application to spiked human plasma

MM Abdelrahman, NM Habib, AA Emam… - Biomedical …, 2020 - Wiley Online Library
Green TLC‐densitometric and RP‐HPLC methods were developed and validated for the
determination of the active prodrug sulfasalazine (SZ), its active metabolite mesalazine (MZ) …

Spectrophotometric method for the simultaneous determination of pyridoxine hydrochloride & phenylephrine hydrochloride via H-point standard addition method

SA Kamel, FM Abdoon - AIP Conference Proceedings, 2022 - pubs.aip.org
This paper aims to study the determination of both binary mixtures including simultaneous
spectrophotometric determination of Pyridoxine hydrochloride (PYR) and Phenylephrine …

Comparative Study of Augmented Classical Least Squares Models for UV Assay of Co-Formulated Antiemetics Together with Related Impurities

MSM Al-Saleem, HW Darwish, IA Naguib, ME Draz - Molecules, 2023 - mdpi.com
The classical least squares (CLS) model and three augmented CLS models are adopted
and validated for the analysis of pyridoxine HCl (PYR), cyclizine HCl (CYC), and meclizine …

Development and validation of two novel chromatographic methods: HPTLC and HPLC for determination of bromhexine hydrochloride in presence of its two impurities

NS Abdelwahab, SM Adly, NW Ali… - Journal of …, 2021 - academic.oup.com
Two simple, sensitive and validated chromatographic methods were developed for
quantitative determination of bromhexine hydrochloride (BHX) in presence of its major …

Ecofriendly single-step HPLC and TLC methods for concurrent analysis of ternary antifungal mixture in their pharmaceutical products

MM Abdelrahman, IA Naguib, HE Zaazaa, HM Nagieb - BMC chemistry, 2023 - Springer
Two accurate, sensitive, and selective methods for simultaneous determination of
miconazole nitrate (MIC), nystatin (NYS), and metronidazole (MET) in pure state or drug …

Spectrofluorimetric approach for quantification of cyclizine in the presence of its toxic impurities in human plasma; in silico study and ADMET calculations

MY Fares, NS Abdelwahab, GM El-Sayed… - Journal of …, 2022 - Springer
Cyclizine (CYZ); an antiemetic compound; is widely misused for its euphoric or hallucinatory
effects, either by oral or intravenous routes. The concomitant abuse of CYZ among addicted …

Comparative chemometric manipulations of UV-spectrophotometric data for the efficient resolution and determination of overlapping signals of cyclizine and its …

MY Fares, NS Abdelwahab, MA Hegazy… - Journal of AOAC …, 2023 - academic.oup.com
Background Cyclizine (CYZ), a commonly used antiemetic drug, has two pharmacopeial
toxic impurities, 1-methylpiperazine (MPZ) and diphenylmethanol (DPM). When CYZ …