Transgenerational plasticity (TGP) occurs when the environment experienced by a parent
influences the development of their offspring. In this article, we develop a framework for …

Our ability to predict how species will respond to human-induced rapid environmental
change (HIREC) may depend upon our understanding of transgenerational plasticity (TGP) …

Highlights•Exercise is a powerful means to maintain health and prevent disease.•Exercise
increases energy expenditure and substrate utilization.•Acute and chronic exercise …

Background Although in all sexually reproducing organisms an individual has a mother and
a father, non-genetic inheritance has been predominantly studied in mothers. Paternal …

Consistent with the paradigm shifting observations of David Barker and colleagues that
revealed a powerful relationship between decreased weight through 2 years of age and …

A significant number of studies have demonstrated that paternal exercise modulates future
generations via effects on the sperm epigenome. However, comprehensive information …

Introduction The prevalence of obesity and associated comorbidities have increased to
epidemic proportions globally. Paternal obesity is an independent risk factor for developing …

Background Parental body mass index (BMI) is associated with pregnancy outcomes. But
the effect of parental prepregnancy BMI on offspring conceived via in vitro fertilization (IVF) …

Key points Paternal obesity negatively influences metabolic outcomes in adult rat offspring.
Maternal voluntary physical activity has previously been reported to improve glucose …

High-fat diet (HFD) feeding in rodents has become an essential tool to critically analyze and
study the pathological effects of obesity, including mitochondrial dysfunction and insulin …