Organs-on-chips are microengineered microfluidic living cell culture devices with
continuously perfused chambers penetrating to cells. By mimicking the biological features of …

Intracellular delivery of nano‐drug‐carriers (NDC) to specific cells, diseased regions, or
solid tumors has entered the era of precision medicine that requires systematic knowledge …

Abstract Blood‐brain‐barrier (BBB) disruption has been associated with a variety of central‐
nervous‐system diseases. In vitro BBB models enable to investigate how the barrier reacts …

Nowadays, implants and prostheses are widely used to repair damaged tissues or to treat
different diseases, but their use is associated with the risk of infection, inflammation and …

As an ideal in vitro model, brain‐on‐chip (BoC) is an important tool to comprehensively
elucidate brain characteristics. However, the in vitro model for the definition scope of BoC …

The human brain and central nervous system (CNS) present unique challenges in drug
development for neurological diseases. One major obstacle is the blood–brain barrier …

Among all the proposed pathogenic mechanisms to understand the etiology of Alzheimer's
disease (AD), increased oxidative stress seems to be a robust and early disease feature …

Following the rapid growth of Organ-on-a-Chip (OoaC) technology, porous membranes
have become essential components for in vitro tissue barrier models. Nonetheless, literature …

The blood-brain barrier (BBB) is a semipermeable endothelial barrier that plays a vital role
in protecting and maintaining proper function of the brain and the central nervous system …

The organ-on-a-chip (OOC) is an in vitro biological model capable of mimicking the
microenvironments of a tissue or cell, working on scales of 10− 9–10− 18 L. The blood–brain …